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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Birc6
baculoviral IAP repeat-containing 6
MGI:1276108
32 phenotypes from 7 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Birc6em1(IMPC)Ccpcz/Birc6+
C57BL/6N-Birc6em1(IMPC)Ccpcz/Ccpcz
abnormal heart morphology J:211773
abnormal retina morphology J:211773
enlarged heart J:211773
increased circulating creatine kinase level J:211773
Birc6em1(IMPC)Ccpcz/Birc6em1(IMPC)Ccpcz
C57BL/6N-Birc6em1(IMPC)Ccpcz/Ccpcz
edema J:211773
no spontaneous movement J:211773
preweaning lethality, complete penetrance J:211773
Birc6Gt(Ex54)Byg/Birc6Gt(Ex54)Byg
involves: 129P2/OlaHsd * C57BL/6
neonatal lethality, complete penetrance J:70273
Birc6Gt(pT1Betageo)2Ruiz/Birc6Gt(pT1Betageo)2Ruiz
involves: 129S2/SvPas * C57BL/6
no abnormal phenotype detected J:85162
Birc6Gt(pT1Betageo)45Flo/Birc6Gt(pT1Betageo)45Flo
involves: 129S2/SvPas * C57BL/6
abnormal placenta morphology J:85162
Birc6m1Anu/Birc6m1Anu
C57BL/6NCrlAnu-Birc6m1Anu
embryonic lethality J:104190
Birc6tm1Nai/Birc6tm1Nai
involves: 129S4/SvJae * C57BL/6J
abnormal angiogenesis J:96768
abnormal cell cycle J:96768
decreased fetal size J:96768
decreased hepatocyte number J:96768
edema J:96768
increased fibroblast apoptosis J:96768
increased thymocyte apoptosis J:96768
lethality throughout fetal growth and development, incomplete penetrance J:96768
neonatal lethality, complete penetrance J:96768
Birc6tm1Sjen/Birc6tm1Sjen
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal definitive hematopoiesis J:94169
abnormal embryonic hematopoiesis J:94169
abnormal placenta labyrinth morphology J:94169
abnormal placenta vasculature J:94169
abnormal placental labyrinth vasculature morphology J:94169
abnormal spongiotrophoblast layer morphology J:94169
abnormal trophoblast layer morphology J:94169
decreased cell proliferation J:94169
fetal growth retardation J:94169
hemorrhage J:94169
intraventricular hemorrhage J:94169
pallor J:94169
perinatal lethality, complete penetrance J:94169
small placenta J:94169

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory