Il12rb2 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il12rb2
interleukin 12 receptor, beta 2
MGI:1270861

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Il12rb2^Ifnm-d/Il12rb2^Ifnm-d Tlr4^lps-del/Tlr4^lps-del C57BL/10ScCr	abnormal dendritic cell physiology	J:91014
	abnormal granulocyte physiology	J:91014
	abnormal immune cell physiology	J:91014
	abnormal macrophage physiology	J:91014
	abnormal NK cell physiology	J:91014
	decreased interferon-gamma secretion	J:70821, J:91014
	increased interleukin-4 secretion	J:91014
	increased susceptibility to bacterial infection	J:70821, J:91014

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23