Lmb1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lmb1
lupus in MRL and B6 F2 cross, QTL 1
MGI:1203738

6 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr involves: C57BL/6-Fas^lpr * MRL-Fas^lpr	enlarged lymph nodes	J:45708
	enlarged spleen	J:45708
	increased anti-double stranded DNA antibody level	J:45708
Lmb1^C57BL/6Scr/Lmb1^C57BL/6Scr MRL.Cg-Lmb1^C57BL/6Scr Fas^lpr	increased CD8-positive, alpha-beta T cell number	J:125557
	increased double-negative T cell number	J:125557
	increased spleen weight	J:125557
Lmb1^C57BL/6Scr/Lmb1^MRL/MpScr involves: C57BL/6-Fas^lpr * MRL-Fas^lpr	enlarged lymph nodes	J:45708
	enlarged spleen	J:45708
	increased anti-double stranded DNA antibody level	J:45708
Lmb1^MRL/MpScr/Lmb1^MRL/MpScr B6.MRL-Lmb1^MRL/MpScr Fas^lpr	enlarged lymph nodes	J:125557

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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