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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
MGI:1203727
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chattm2(cre)Lowl/Chat+
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NCr 		abnormal inhibitory postsynaptic currents J:202884
Plxna2tm1Hfu/Plxna2+
Sema6aGt(KST069)Byg/Sema6a+
involves: 129P2/OlaHsd * C57BL/6 * CBA 		ectopic cerebellar granule cells J:135408
Plxna2tm1Hfu/Plxna2tm1Hfu
Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal hippocampal mossy fiber morphology J:160509
ectopic cerebellar granule cells J:135408
normal nervous system phenotype J:135421
Plxna2tm1Hfu/Plxna2tm1Hfu
Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj 		abnormal amacrine cell morphology J:202884
abnormal dendrite morphology J:202884
abnormal retina inner plexiform layer morphology J:202884
Plxna4tm1Matl/Plxna4+
Sema6aGt(KST069)Byg/Sema6a+
involves: 129P2/OlaHsd 		decreased sensory neuron number J:172268
Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
Sema6btm1Hfu/Sema6btm1Hfu
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		abnormal hippocampal mossy fiber morphology J:160509
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory