Tcf7l2em1Nobr/Tcf7l2+
involves: CD-1
|
decreased body weight |
J:175874
|
decreased circulating glucose level |
J:175874
|
decreased circulating insulin level |
J:175874
|
decreased lean body mass |
J:175874
|
decreased locomotor activity |
J:175874
|
decreased total body fat amount |
J:175874
|
normal
homeostasis/metabolism phenotype |
J:175874
|
hypoglycemia |
J:175874
|
improved glucose tolerance |
J:175874
|
polyphagia |
J:175874
|
Tcf7l2em1Nobr/Tcf7l2em1Nobr
involves: CD-1
|
absent gastric milk in neonates |
J:175874
|
decreased birth body size |
J:175874
|
hypoglycemia |
J:175874
|
neonatal lethality, complete penetrance |
J:175874
|
Tcf7l2em2Nobr/Tcf7l2+
involves: CD-1
|
decreased body weight |
J:175874
|
decreased circulating glucose level |
J:175874
|
decreased circulating insulin level |
J:175874
|
decreased lean body mass |
J:175874
|
decreased locomotor activity |
J:175874
|
decreased total body fat amount |
J:175874
|
normal
homeostasis/metabolism phenotype |
J:175874
|
hypoglycemia |
J:175874
|
improved glucose tolerance |
J:175874
|
polyphagia |
J:175874
|
Tcf7l2em2Nobr/Tcf7l2em2Nobr
involves: CD-1
|
absent gastric milk in neonates |
J:175874
|
decreased birth body size |
J:175874
|
hypoglycemia |
J:175874
|
neonatal lethality, complete penetrance |
J:175874
|
Tcf7l2em3Nobr/Tcf7l2em3Nobr
involves: CD-1
|
absent gastric milk in neonates |
J:175874
|
decreased birth body size |
J:175874
|
hypoglycemia |
J:175874
|
neonatal lethality, complete penetrance |
J:175874
|
Tcf7l2m1Btlr/Tcf7l2m1Btlr
C57BL/6J-Tcf7l2m1Btlr
|
increased susceptibility to induced colitis |
J:267536
|
Tcf7l2tm1(EGFP/cre)Mrc/Tcf7l2tm2.1Mrc
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl
|
abnormal crypts of Lieberkuhn morphology |
J:170088
|
decreased body size |
J:170088
|
normal
neoplasm |
J:170088
|
Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm1.1(EGFP/cre)Mrc
involves: 129S1/Sv * 129X1/SvJ
|
abnormal colon goblet cell morphology |
J:170088
|
abnormal colon morphology |
J:170088
|
abnormal crypts of Lieberkuhn morphology |
J:170088
|
abnormal enterocyte proliferation |
J:170088
|
abnormal intestinal enteroendocrine cell morphology |
J:170088
|
abnormal intestine morphology |
J:170088
|
abnormal small intestine goblet cell morphology |
J:170088
|
abnormal small intestine morphology |
J:170088
|
absent gastric milk in neonates |
J:170088
|
decreased birth weight |
J:170088
|
embryo tissue necrosis |
J:170088
|
neonatal lethality, complete penetrance |
J:170088
|
Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm2.1Mrc
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl
|
abnormal colon morphology |
J:170088
|
abnormal crypts of Lieberkuhn morphology |
J:170088
|
abnormal enterocyte proliferation |
J:170088
|
abnormal intestinal enteroendocrine cell morphology |
J:170088
|
abnormal intestinal goblet cell morphology |
J:170088
|
abnormal intestine morphology |
J:170088
|
abnormal small intestine morphology |
J:170088
|
absent gastric milk in neonates |
J:170088
|
decreased birth weight |
J:170088
|
embryo tissue necrosis |
J:170088
|
neonatal lethality, complete penetrance |
J:170088
|
Tcf7l2tm1.1(EGFP/cre)Mrc/Tcf7l2tm2.2Mrc
involves: 129S1/Sv * 129X1/SvJ
|
abnormal colon morphology |
J:170088
|
abnormal crypts of Lieberkuhn morphology |
J:170088
|
abnormal enterocyte proliferation |
J:170088
|
abnormal intestinal enteroendocrine cell morphology |
J:170088
|
abnormal intestinal goblet cell morphology |
J:170088
|
abnormal intestine morphology |
J:170088
|
abnormal small intestine morphology |
J:170088
|
absent gastric milk in neonates |
J:170088
|
decreased birth weight |
J:170088
|
embryo tissue necrosis |
J:170088
|
neonatal lethality, complete penetrance |
J:170088
|
Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2+
C57BL/6-Tcf7l2tm1a(EUCOMM)Wtsi
|
abnormal glucose homeostasis |
J:190447
|
abnormal hepatocyte physiology |
J:190447
|
abnormal response/metabolism to endogenous compounds |
J:190447
|
impaired glucose tolerance |
J:190447
|
increased circulating glucose level |
J:190447
|
Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2+
C57BL/6N-Tcf7l2tm1a(EUCOMM)Wtsi/Wtsi
|
decreased total body fat amount |
J:211773
|
increased bone mineral content |
J:211773
|
increased bone mineral density |
J:211773
|
increased lean body mass |
J:211773
|
increased mean platelet volume |
J:211773
|
increased red blood cell distribution width |
J:211773
|
Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2tm1a(EUCOMM)Wtsi
C57BL/6-Tcf7l2tm1a(EUCOMM)Wtsi
|
lethality, complete penetrance |
J:190447
|
Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2tm1a(EUCOMM)Wtsi
C57BL/6N-Tcf7l2tm1a(EUCOMM)Wtsi/Wtsi
|
abnormal basilar artery morphology |
J:239583
|
abnormal cecum position |
J:239583
|
abnormal elbow joint morphology |
J:239583
|
abnormal eye muscle morphology |
J:239583
|
abnormal forebrain morphology |
J:239583
|
abnormal inferior vena cava morphology |
J:239583
|
abnormal inferior vena cava topology |
J:239583
|
abnormal Mullerian duct morphology |
J:239583
|
abnormal nasal septum morphology |
J:239583
|
abnormal neurohypophysis morphology |
J:239583
|
abnormal pulmonary valve cusp morphology |
J:239583
|
abnormal umbilical vein topology |
J:239583
|
abnormal ureter topology |
J:239583
|
abnormal vertebral artery morphology |
J:239583
|
abnormal vertebral artery topology |
J:239583
|
abnormal Wolffian duct morphology |
J:239583
|
absent ductus venosus valve |
J:239583
|
absent kidney |
J:239583
|
basisphenoid bone foramen |
J:239583
|
common truncal valve |
J:239583
|
dilated liver sinusoidal space |
J:239583
|
double outlet right ventricle |
J:239583
|
duplication of ductus venosus |
J:239583
|
fusion of vertebral arches |
J:239583
|
heterochrony |
J:239583
|
muscular ventricular septal defect |
J:239583
|
perimembraneous ventricular septal defect |
J:239583
|
preweaning lethality, complete penetrance |
J:211773
|
retroesophageal right subclavian artery |
J:239583
|
symmetric azygos veins |
J:239583
|
vertebral fusion |
J:239583
|
Tcf7l2tm1Cle/Tcf7l2tm1Cle
involves: 129P2/OlaHsd
|
abnormal craniofacial development |
J:86317
|
abnormal enterocyte morphology |
J:48968
|
abnormal intestinal epithelium morphology |
J:48968
|
abnormal pituitary intermediate lobe morphology |
J:86317
|
normal
cellular phenotype |
J:98680
|
decreased enterocyte cell number |
J:48968
|
enlarged adenohypophysis |
J:86317
|
enlarged pituitary gland |
J:86317
|
neonatal lethality, complete penetrance |
J:48968
|
Tcf7l2tm1Geno/Tcf7l2tm1Geno Tg(Pdx1-cre)89.1Dam/0
involves: C57BL/6 * CBA
|
decreased insulin secretion |
J:189204
|
decreased pancreatic beta cell mass |
J:189204
|
impaired glucose tolerance |
J:189204
|
increased circulating insulin level |
J:189204
|
Tcf7l2tm2.1Cle/Tcf7l2tm2.1Cle Tg(Vil1-cre/ERT2)23Syr/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
abnormal enterocyte proliferation |
J:185753
|
abnormal intestine development |
J:185753
|
abnormal small intestine goblet cell morphology |
J:185753
|
absent Paneth cells |
J:185753
|
decreased Paneth cell number |
J:185753
|
ectopic Paneth cells |
J:185753
|
increased enterocyte apoptosis |
J:185753
|
Tcf7l2tm2.2Mrc/Tcf7l2tm2.2Mrc
involves: 129S1/Sv
|
abnormal colon morphology |
J:170088
|
abnormal crypts of Lieberkuhn morphology |
J:170088
|
abnormal enterocyte proliferation |
J:170088
|
abnormal intestinal enteroendocrine cell morphology |
J:170088
|
abnormal intestinal goblet cell morphology |
J:170088
|
abnormal intestine morphology |
J:170088
|
abnormal small intestine morphology |
J:170088
|
absent gastric milk in neonates |
J:170088
|
decreased birth weight |
J:170088
|
embryo tissue necrosis |
J:170088
|
neonatal lethality, complete penetrance |
J:170088
|
Tg(Krt14-Tcf7l2)1Efu/0
Not Specified
|
abnormal epidermal layer morphology |
J:155012
|
eyelids open at birth |
J:155012
|
Tg(Krt14-Tcf7l2*)2Efu/0
Not Specified
|
eyelids open at birth |
J:155012
|
Tg(Krt14-Tcf7l2*)3Efu/0
Not Specified
|
no abnormal phenotype detected |
J:155012
|
Tg(RP11-466I19/Tcf7l2)1Nobr/0
involves: CD-1
|
decreased food intake |
J:175874
|
normal
homeostasis/metabolism phenotype |
J:175874
|
impaired glucose tolerance |
J:175874
|