Tnfsf12 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
MGI:1196259

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(SERPINA1-Tnfsf12)1Biib/0 involves: C57BL/6 * DBA/2	abnormal liver physiology	J:100907
	abnormal oval cell morphology	J:100907
	abnormal oval cell physiology	J:100907
	increased hepatocyte apoptosis	J:100907
Tnfsf12^tm1Ash/Tnfsf12^tm1Ash B6.129-Tnfsf12^tm1Ash	abnormal cytokine secretion	J:104801
	abnormal immune system organ morphology	J:104801
	abnormal leukocyte morphology	J:104801
	decreased interleukin-10 secretion	J:104801
	enlarged lymph nodes	J:104801
	enlarged spleen	J:104801
	increased double-positive T cell number	J:104801
	increased interferon-gamma secretion	J:104801
	increased interleukin-12 secretion	J:104801
	increased memory T cell number	J:104801
	increased NK cell number	J:104801
	increased susceptibility to bacterial infection	J:104801
	increased T-helper 1 cell number	J:104801

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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