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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
MGI:1194488
29 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Agrptm1(cre)Lowl/Agrp+
Slc32a1tm1Lowl/Slc32a1tm1Lowl
involves: 129S6/SvEvTac * C57BL/6
abnormal food intake J:140858
abnormal inhibitory postsynaptic currents J:140858
decreased body weight J:140858
decreased respiratory quotient J:140858
decreased susceptibility to diet-induced obesity J:140858
decreased total body fat amount J:140858
increased locomotor activity J:140858
increased oxygen consumption J:140858
Agrptm1(cre)Lowl/Agrp+
Slc32a1tm1Lowl/Slc32a1tm1Lowl
Tg(Pomc1-hrGFP)1Lowl/0
involves: 129S6/SvEvTac * FVB/N
normal nervous system phenotype J:174691
Slc32a1tm1.1Bgc/Slc32a1tm1.1Bgc
involves: 129X1/SvJ
abnormal adipose tissue distribution J:158888
cleft secondary palate J:158888
failure of palatal shelf elevation J:158888
hunched posture J:158888
perinatal lethality, complete penetrance J:158888
respiratory failure J:158888
umbilical hernia J:158888
Slc32a1tm1Bros/Slc32a1tm1Bros
involves: 129P2/OlaHsd
abnormal inhibitory postsynaptic currents J:122318
cleft secondary palate J:122318
decreased neurotransmitter release J:122318
hunched posture J:122318
muscle hypertonia J:122318
no spontaneous movement J:122318
omphalocele J:122318
perinatal lethality, complete penetrance J:122318
Slc32a1tm1Yyan/Slc32a1tm1Yyan
Not Specified
abnormal inhibitory postsynaptic potential J:122055
abnormal nerve fiber response J:122055
abnormal nervous system electrophysiology J:122055
cleft palate J:122055
neonatal lethality, complete penetrance J:122055
omphalocele J:122055
primary atelectasis J:122055
respiratory failure J:122055
Slc32a1tm2(cre)Lowl/Slc32a1+
involves: 129S6/SvEvTac
no abnormal phenotype detected J:174691
Slc32a1tm2(cre)Lowl/Slc32a1tm2(cre)Lowl
either: B6J.129S6(FVB)-Slc32a1tm2(cre)Lowl or (involves: 129S6/SvEvTac * C57BL/6J * FVB/N)
abnormal inhibitory postsynaptic currents J:308516
increased kindling response J:308516
tonic-clonic seizures J:308516

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory