Tnfsf11 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfsf11
tumor necrosis factor (ligand) superfamily, member 11
MGI:1100089

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd40^tm1Kik/Cd40^tm1Kik Tnfsf11^tm1Pngr/Tnfsf11^tm1Pngr involves: 129P2/OlaHsd	abnormal thymus epithelium morphology	J:173115
Ltbr^tm1Mmat/Ltbr^tm1Mmat Tnfsf11^tm1Pngr/Tnfsf11^tm1Pngr involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal thymus epithelium morphology	J:173115
Tg(Bglap2-TAg)1Rkho/0 Tnfsf11^tm1Pngr/Tnfsf11⁺ involves: 129P2/OlaHsd * FVB/N	increased osteosarcoma incidence	J:234128
Tg(Bglap2-TAg)1Rkho/0 Tnfsf11^tm1Pngr/Tnfsf11^tm1Pngr involves: 129P2/OlaHsd * FVB/N	abnormal femur morphology	J:234128
	decreased osteosarcoma incidence	J:234128
Tg(TNFSF11)5516Edou/0 Tnfsf11^tles/Tnfsf11^tles involves: 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal tooth eruption	J:233240
	absent lymph nodes	J:233240
	normal mortality/aging	J:233240
	normal skeleton phenotype	J:233240
Tg(TNFSF11)5519Edou/0 Tnfsf11^tles/Tnfsf11^tles involves: 129S6/SvEvTac * C57BL/6J * CBA/J	no abnormal phenotype detected	J:233240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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