Atxn3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atxn3
ataxin 3
MGI:1099442

16 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atxn3^em1Jhus/Atxn3⁺ C57BL/6-Atxn3^em1Jhus	abnormal gait	J:338892
	decreased Purkinje cell number	J:338892
	impaired coordination	J:338892
	kyphosis	J:338892
	neuronal intranuclear inclusions	J:338892
	weight loss	J:338892
Atxn3^em1Jhus/Atxn3^em1Jhus C57BL/6-Atxn3^em1Jhus	abnormal gait	J:338892
	decreased body size	J:338892
	decreased Purkinje cell number	J:338892
	enhanced coordination	J:338892
	impaired balance	J:338892
	impaired coordination	J:338892
	kyphosis	J:338892
	neuronal intranuclear inclusions	J:338892
	weight loss	J:338892
Atxn3^em2Jhus/Atxn3⁺ C57BL/6-Atxn3^em2Jhus	no abnormal phenotype detected	J:338892
Atxn3^{tm1a(KOMP)Wtsi}/Atxn3^{tm1a(KOMP)Wtsi} C57BL/6N-Atxn3^{tm1a(KOMP)Wtsi}/Wtsi	decreased circulating fructosamine level	J:211773
	increased anti-nuclear antigen antibody level	J:211773
	increased circulating aspartate transaminase level	J:211773
Atxn3^tm1Isch/Atxn3^tm1Isch C57BL/6-Atxn3^tm1Isch	normal behavior/neurological phenotype	J:145048
	decreased exploration in new environment	J:145048
	decreased vertical activity	J:145048

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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