Tmem38b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem38b
transmembrane protein 38B
MGI:1098718

31 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem38b^em1(IMPC)Mbp/Tmem38b⁺ C57BL/6NCrl-Tmem38b^em1(IMPC)Mbp/MbpMmucd	abnormal lens morphology	J:211773
	abnormal optic disk morphology	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	fused cornea and lens	J:211773
	persistence of hyaloid vascular system	J:211773
Tmem38b^em1(IMPC)Mbp/Tmem38b^em1(IMPC)Mbp C57BL/6NCrl-Tmem38b^em1(IMPC)Mbp/MbpMmucd	preweaning lethality, complete penetrance	J:211773
Tmem38b^tm1Hta/Tmem38b^tm1Hta involves: 129S4/SvJae	neonatal lethality	J:122817
Tmem38b^tm1Hta/Tmem38b^tm1Hta involves: 129S4/SvJae * C57BL/6J	abnormal alveolar lamellar body morphology	J:150355
	abnormal calcium ion homeostasis	J:150355
	abnormal lung development	J:150355
	abnormal lung saccule morphology	J:150355
	abnormal pulmonary alveolus epithelial cell morphology	J:150355
	abnormal respiratory system physiology	J:150355
	abnormal surfactant composition	J:150355
	abnormal surfactant secretion	J:150355
	abnormal type II pneumocyte morphology	J:150355
	acidosis	J:150355
	atelectasis	J:150355
	cyanosis	J:150355
	decreased alveolar lamellar body number	J:150355
	hypoxia	J:150355
	impaired lung alveolus development	J:150355
	neonatal lethality, complete penetrance	J:150355
	pulmonary vascular congestion	J:150355
	respiratory distress	J:150355
	respiratory failure	J:150355
	small alveolar lamellar bodies	J:150355
	thick pulmonary interalveolar septum	J:150355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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