About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ifnar2
interferon (alpha and beta) receptor 2
MGI:1098243
17 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ifnar2m1Btlr/Ifnar2m1Btlr
C57BL/6J-Ifnar2m1Btlr 		abnormal macrophage physiology J:147329
decreased interferon-alpha secretion J:147329
decreased interferon-beta secretion J:147329
increased susceptibility to Adenoviridae infection J:147329
increased susceptibility to Herpesvirales infection J:147329
increased susceptibility to Orthomyxoviridae infection J:147329
increased susceptibility to Riboviria infection J:147329
Ifnar2tm1Pjh/Ifnar2tm1Pjh
B6.Cg-Ifnar2tm1Pjh 		decreased NK cell number J:125812
impaired natural killer cell mediated cytotoxicity J:125812
increased incidence of induced tumors J:125812
increased incidence of tumors by chemical induction J:125812
Ifnar2tm1Pjh/Ifnar2tm1Pjh
involves: C57BL/6 		abnormal CD4-positive, alpha-beta T cell physiology J:132662
abnormal cytotoxic T cell physiology J:132662
decreased IgG1 level J:132662
decreased IgG2a level J:132662
decreased IgG level J:132662
decreased interferon-gamma secretion J:132662
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory