C3ar1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C3ar1
complement component 3a receptor 1
MGI:1097680

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
C3ar1^tm1Cge/C3ar1^tm1Cge C5ar1^tm1Cge/C5ar1^tm1Cge B6.Cg-C3ar1^tm1Cge C5ar1^tm1Cge	abnormal c-wave shape	J:214214
	abnormal electroretinogram waveform feature	J:214214
	abnormal photoreceptor outer segment disc membrane morphology	J:214214
	abnormal retina horizontal cell morphology	J:214214
	abnormal retina pigment epithelium morphology	J:214214
	abnormal retina rod bipolar cell morphology	J:214214
	decreased a-wave amplitude	J:214214
	decreased b-wave amplitude	J:214214
	decreased circulating free fatty acids level	J:214214
	decreased circulating phospholipid level	J:214214
	disorganized retina outer nuclear layer	J:214214
	increased retina apoptosis	J:214214
	increased susceptibility to age-related retinal degeneration	J:214214
	thin retina inner nuclear layer	J:214214
	thin retina outer nuclear layer	J:214214
C3ar1^tm1Raw/C3ar1^tm1Raw Cpn1^tm1Raw/Cpn1^tm1Raw B6.129-C3ar1^tm1Raw Cpn1^tm1Raw	increased acute inflammation	J:148315

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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