Ptpro Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptpro
protein tyrosine phosphatase receptor type O
MGI:1097152

7 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptpro^tm1Dgen/Ptpro^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to pharmacologically induced seizures	J:101679
Ptpro^tm1Shs/Ptpro^tm1Shs involves: 129	no abnormal phenotype detected	J:104881
Ptpro^tm1Wig/Ptpro^tm1Wig involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cardiovascular system physiology	J:65903
	abnormal podocyte foot process morphology	J:65903
	abnormal podocyte morphology	J:65903
	abnormal renal glomerulus morphology	J:65903
	decreased renal glomerular filtration rate	J:65903

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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