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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
MGI:1096317
34 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Eef1a2em1Abb/Eef1a2em1Abb
C57BL/6JCrl-Eef1a2em1Abb
abnormal spinal cord morphology J:296080
decreased body weight J:296080
gliosis J:296080
neurodegeneration J:296080
premature death J:296080
sporadic seizures J:296080
Eef1a2em#Abb/Eef1a2+
C57BL/6JCrl-Eef1a2em#Abb
abnormal behavior J:296080
decreased body weight J:296080
decreased grip strength J:296080
decreased skeletal muscle mass J:296080
impaired coordination J:296080
Eef1a2em#Abb/Eef1a2em#Abb
C57BL/6JCrl-Eef1a2em#Abb
abnormal behavior J:296080
abnormal spinal cord morphology J:296080
decreased body weight J:296080
gliosis J:296080
neurodegeneration J:296080
premature death J:296080
Eef1a2wst/Eef1a2wst
B6C3Fe a/a-Eef1a2wst/J
chromosomal instability J:6766
decreased plasma cell number J:7903
decreased spleen weight J:6766
decreased susceptibility to type IV hypersensitivity reaction J:6766
decreased thymus weight J:6766
demyelination J:6766
increased cellular sensitivity to gamma-irradiation J:6766
lymphoid hypoplasia J:6766
paraparesis J:24753
premature death J:24753
Purkinje cell degeneration J:6766
slow postnatal weight gain J:6766
small lymph nodes J:6766
tremors J:24753
weight loss J:24753
Eef1a2wst/Eef1a2wst
involves: HRS/J
abnormal endplate potential J:104855
abnormal innervation pattern to muscle J:104855
abnormal motor neuron morphology J:104855
abnormal muscle morphology J:104855
abnormal neuromuscular synapse morphology J:104855
abnormal neurotransmitter uptake J:104855
abnormal spinal cord ventral horn morphology J:104855
decreased neurotransmitter release J:104855
gliosis J:104855
impaired coordination J:104855
motor neuron degeneration J:104855
Eef1a2wst/Eef1a2wst
Not Specified
thymus atrophy J:50410

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory