Plk3 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plk3
polo like kinase 3
MGI:109604

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plk3^tm1Dai/Plk3^tm1Dai involves: 129S4/SvJae * C57BL/6	abnormal tumor morphology	J:136425
	increased leiomyosarcoma incidence	J:136425
	increased liver tumor incidence	J:136425
	increased lung adenocarcinoma incidence	J:136425
	increased lung tumor incidence	J:136425
	increased tumor growth/size	J:136425
	increased tumor incidence	J:136425
Plk3^tm1Elan/Plk3^tm1Elan C57BL/6-Plk3^tm1Elan	lethality, complete penetrance	J:201467
Plk3^tm1Elan/Plk3^tm1Elan involves: 129S6/SvEvTac * C57BL/6	normal mortality/aging	J:201467
Plk3^tm1Pjs/Plk3^tm1Pjs involves: 129S6/SvEvTac * Black Swiss	abnormal cell cycle	J:175096
	abnormal cell cycle checkpoint function	J:175096
	normal neoplasm	J:175096
	polyploidy	J:175096

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24