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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		F7
coagulation factor VII
MGI:109325
17 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
F7tm1(tTA,tetO-F7)Edr/F7tm1(tTA,tetO-F7)Edr
B6.129X1-F7tm1(tTA,tetO-F7)Edr 		abnormal blood coagulation J:144540
abnormal circulating protein level J:144540
cardiac fibrosis J:144540
heart hemorrhage J:144540
increased partial thromboplastin time J:144540
increased prothrombin time J:144540
F7tm1(tTA,tetO-F7)Edr/F7tm1(tTA,tetO-F7)Edr
involves: 129X1/SvJ * C57BL/6 		normal mortality/aging J:144540
F7tm1(tTA,tetO-F7)Edr/F7tm1Pec
involves: 129X1/SvJ * C57BL/6 		premature death J:144540
F7tm1b(EUCOMM)Hmgu/F7+
C57BL/6N-F7tm1b(EUCOMM)Hmgu/H 		abnormal snout morphology J:211773
decreased bone mineral content J:211773
decreased lean body mass J:211773
increased total body fat amount J:211773
F7tm1b(EUCOMM)Hmgu/F7tm1b(EUCOMM)Hmgu
C57BL/6N-F7tm1b(EUCOMM)Hmgu/H 		preweaning lethality, incomplete penetrance J:211773
F7tm1Pec/F7+
involves: 129X1/SvJ * C57BL/6J 		no abnormal phenotype detected J:44294
F7tm1Pec/F7tm1Pec
involves: 129X1/SvJ * C57BL/6J 		normal cardiovascular system phenotype J:44294
internal hemorrhage J:44294
neonatal lethality, incomplete penetrance J:44294
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory