Cd59a Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd59a
CD59a antigen
MGI:109177

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Bres/Apoe^tm1Bres Cd59a^tm1Bpm/Cd59a^tm1Bpm involves: 129 * 129P2/OlaHsd	increased susceptibility to atherosclerosis	J:158457
	vascular smooth muscle hyperplasia	J:158457
	vascular smooth muscle hypoplasia	J:158457
C3^tm1Crr/C3^tm1Crr Cd59a^tm1Bpm/Cd59a^tm1Bpm B6.129-Cd59a^tm1Bpm C3^tm1Crr	increased T cell proliferation	J:122201
Cd55^tm1Song/Cd55^tm1Song Cd59a^tm1Bpm/Cd59a^tm1Bpm B6.129-Cd55^tm1Song Cd59a^tm1Bpm	abnormal complement pathway	J:113567
	abnormal muscle morphology	J:113567
	decreased grip strength	J:113567
	increased susceptibility to experimental autoimmune myasthenia gravis	J:113567
	increased susceptibility to induced morbidity/mortality	J:113567
	myositis	J:113567
	weight loss	J:113567
Cd59a^tm1Song/Cd59a^tm1Song Cd55^tm1Song/Cd55^tm1Song involves: 129S6/SvEvTac * C57BL/6	abnormal complement pathway	J:76578
	normal hematopoietic system phenotype	J:76578

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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