Tfpi2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tfpi2
tissue factor pathway inhibitor 2
MGI:108543

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tfpi2^{em1(IMPC)Kmpc}/Tfpi2^{em1(IMPC)Kmpc} C57BL/6NTac-Tfpi2^{em1(IMPC)Kmpc}/Kmpc	hyperactivity	J:211773
Tfpi2^tm1Dgen/Tfpi2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	normal immune system phenotype	J:301794
	increased circulating interleukin-6 level	J:301794
	increased circulating interleukin-10 level	J:301794
	increased interleukin-10 secretion	J:301794
	increased susceptibility to bacterial infection	J:301794
	increased susceptibility to bacterial infection induced morbidity/mortality	J:301794

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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