Gcm1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gcm1
glial cells missing homolog 1
MGI:108045

18 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gcm1^tm1Hoso/Gcm1^tm1Hoso either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * CD-1)	abnormal neuron differentiation	J:175891
	embryonic lethality during organogenesis, complete penetrance	J:175891
Gcm1^tm1Jcc/Gcm1⁺ involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal placenta fetal blood space morphology	J:186528
	abnormal placenta labyrinth morphology	J:186528
	abnormal placental labyrinth vasculature morphology	J:186528
	abnormal syncytiotrophoblast morphology	J:186528
	embryo tissue necrosis	J:186528
	increased cell proliferation	J:186528
	increased mean systemic arterial blood pressure	J:186528
	increased placenta intervillous maternal lacunae size	J:186528
	thick placenta labyrinth	J:186528
Gcm1^tm1Jcc/Gcm1^tm1Jcc involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal chorionic plate morphology	J:63123
	absent placental labyrinth	J:63123
	decreased embryo size	J:63123
	embryonic lethality, complete penetrance	J:63123
Gcm1^tm1Ral/Gcm1^tm1Ral involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:77274
Gcm1^tm1Weg/Gcm1^tm1Weg involves: 129S1/Sv * 129X1/SvJ	abnormal extraembryonic tissue morphology	J:61094
Gcm1^tm1Weg/Gcm1^tm1Weg involves: 129S1/Sv * 129X1/SvJ	prenatal lethality	J:61094

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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