74 phenotypes from 7 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nkx3-2tm1(cre)Wez/Nkx3-2tm1(cre)Wez involves: 129S7/SvEvBrd * C57BL/6	abnormal skeleton morphology	J:148724
	abnormal vertebral column morphology	J:148724
	absent basioccipital bone	J:148724
	absent basisphenoid bone	J:148724
Nkx3-2tm1.1Tlu/Nkx3-2tm1.1Tlu either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal basioccipital bone morphology	J:55583
	abnormal basisphenoid bone morphology	J:55583
	abnormal bone ossification	J:55583
	abnormal cartilage development	J:55583
	abnormal cervical atlas morphology	J:55583
	abnormal cranium morphology	J:55583
	abnormal intervertebral disk morphology	J:55583
	abnormal neurocranium morphology	J:55583
	abnormal thoracic cavity morphology	J:55583
	abnormal vertebrae morphology	J:55583
	abnormal vertebral arch morphology	J:55583
	abnormal vertebral body development	J:55583
	abnormal vertebral body morphology	J:55583
	absent spleen	J:55583
	absent supraoccipital bone	J:55583
	axial skeleton hypoplasia	J:55583
	barrel chest	J:55583
	decreased body height	J:55583
	normal limbs/digits/tail phenotype	J:55583
	neonatal lethality, complete penetrance	J:55583
	short tail	J:55583
	short vertebral column	J:55583
	small exoccipital bone	J:55583
	small vertebrae	J:55583
Nkx3-2tm1Bobh/Nkx3-2+ involves: 129P2/OlaHsd * C57BL/6	abnormal malleus morphology	J:88584
	abnormal middle ear morphology	J:88584
	abnormal middle ear ossicle morphology	J:88584
	gonial bone hypoplasia	J:88584
	kinked tail	J:57112
Nkx3-2tm1Bobh/Nkx3-2tm1Bobh involves: 129P2/OlaHsd * C57BL/6	abnormal axial skeleton morphology	J:57112
	abnormal basicranium morphology	J:57112
	abnormal cartilage development	J:79198
	abnormal cartilage morphology	J:79198
	abnormal cervical vertebrae morphology	J:57112
	abnormal digestive organ placement	J:93234
	abnormal left-right axis patterning	J:93234
	abnormal malleus morphology	J:88584
	abnormal middle ear ossicle morphology	J:88584
	abnormal notochord morphology	J:57112
	abnormal pancreas development	J:93234
	abnormal rib morphology	J:57112
	abnormal sclerotome morphology	J:57112
	abnormal thoracic vertebrae morphology	J:57112
	abnormal tympanic ring morphology	J:88584
	abnormal vertebrae morphology	J:57112
	abnormal vertebral arch development	J:57112
	absent gonial bone	J:88584
	absent intervertebral disk	J:57112
	absent spleen	J:57112
	absent vertebral body	J:57112
	basioccipital bone hypoplasia	J:57112
	decreased body height	J:57112
	kinked tail	J:79198
	neonatal lethality, complete penetrance	J:79198, J:93802
	perinatal lethality, complete penetrance	J:57112
	short tail	J:57112
	small basioccipital bone	J:57112
	small basisphenoid bone	J:57112
	small caudal vertebrae	J:57112
	thick tail	J:57112
	vertebral compression	J:57112
Nkx3-2tm1Tlu/Nkx3-2+ either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal vertebrae morphology	J:55583
Nkx3-2tm1Tlu/Nkx3-2tm1Tlu either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal basioccipital bone morphology	J:55583
	abnormal basisphenoid bone morphology	J:55583
	abnormal bone ossification	J:55583
	abnormal cartilage development	J:55583
	abnormal cranium morphology	J:55583
	abnormal intervertebral disk morphology	J:55583
	abnormal neurocranium morphology	J:55583
	abnormal thoracic cavity morphology	J:55583
	abnormal vertebrae morphology	J:55583
	abnormal vertebral arch morphology	J:55583
	abnormal vertebral body development	J:55583
	abnormal vertebral body morphology	J:55583
	absent arcus anterior	J:55583
	absent spleen	J:55583
	absent supraoccipital bone	J:55583
	axial skeleton hypoplasia	J:55583
	barrel chest	J:55583
	decreased body height	J:55583
	normal limbs/digits/tail phenotype	J:55583
	neonatal lethality, complete penetrance	J:55583
	short tail	J:55583
	short vertebral column	J:55583
	small exoccipital bone	J:55583
	small vertebrae	J:55583
Nkx3-2tm1Tno/Nkx3-2tm1Tno involves: 129S4/SvJae * C57BL/6J	abnormal axial skeleton morphology	J:77612
	abnormal cartilage development	J:77612
	abnormal cervical atlas morphology	J:77612
	abnormal cervical axis morphology	J:77612
	abnormal cervical vertebrae morphology	J:77612
	abnormal craniofacial bone morphology	J:77612
	abnormal digestive system morphology	J:77612
	abnormal exoccipital bone morphology	J:77612
	abnormal hyoid bone body morphology	J:77612
	abnormal lumbar vertebrae morphology	J:77612
	abnormal notochord morphology	J:77612
	abnormal odontoid process morphology	J:77612
	abnormal sclerotome morphology	J:77612
	abnormal supraoccipital bone morphology	J:77612
	abnormal thoracic vertebrae morphology	J:77612
	abnormal vertebrae development	J:77612
	abnormal vertebral arch morphology	J:77612
	abnormal vertebral body morphology	J:77612
	absent intervertebral disk	J:77612
	absent spleen	J:77612
	absent ventral tubercle of atlas	J:77612
	basioccipital bone hypoplasia	J:77612
	basisphenoid bone hypoplasia	J:77612
	decreased body length	J:77612
	decreased cell proliferation	J:77612
	kinked tail	J:77612
	neonatal lethality, complete penetrance	J:77612
	persistence of notochord tissue	J:77612
	respiratory distress	J:77612
	vertebral body hypoplasia	J:77612
Nkx3-2tm3.1(cre)Tlu/Nkx3-2tm3.1(cre)Tlu involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:178893
Nkx3-2tm4.1(cre)Tlu/Nkx3-2tm4.1(cre)Tlu involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:178893