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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gadd45b
growth arrest and DNA-damage-inducible 45 beta
MGI:107776
17 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gadd45btm1Daa/Gadd45btm1Daa
involves: 129X1/SvJ * C57BL/6 		abnormal bone marrow cell morphology/development J:102680
Gadd45btm1Flv/Gadd45btm1Flv
B6.129S6-Gadd45btm1Flv 		abnormal T-helper 1 physiology J:118837
glomerulonephritis J:118837
increased interferon-gamma secretion J:118837
increased susceptibility to experimental autoimmune encephalomyelitis J:118837
increased T cell proliferation J:118837
renal glomerular immunoglobulin deposits J:118837
spleen hyperplasia J:118837
Gadd45btm1Flv/Gadd45btm1Flv
involves: 129S6/SvEvTac 		abnormal CD4-positive, alpha-beta T cell physiology J:87396
abnormal dendritic cell physiology J:87396
abnormal T-helper 1 cell differentiation J:87396
abnormal T-helper 1 physiology J:87396
abnormal T-helper 2 physiology J:87396
decreased interferon-gamma secretion J:87396
decreased interleukin-2 secretion J:87396
decreased interleukin-4 secretion J:87396
decreased interleukin-6 secretion J:87396
decreased interleukin-12 secretion J:87396
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory