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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lefty1
left right determination factor 1
MGI:107405
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cer1tm1Bhr/Cer1tm1Bhr
Lefty1tm1Hmd/Lefty1tm1Hmd
involves: 129P2/OlaHsd * 129S7/SvEvBrd * CD-1 		abnormal amniotic cavity morphology J:81339
abnormal embryonic epiblast morphology J:81339
abnormal lateral plate mesoderm morphology J:81339
abnormal paraxial mesoderm morphology J:81339
abnormal primitive streak formation J:81339
abnormal primitive streak morphology J:81339
absent somites J:81339
embryonic lethality during organogenesis, incomplete penetrance J:81339
embryonic-extraembryonic boundary constriction J:81339
Cer1tm1Bhr/Cer1tm1Bhr
Lefty1tm1Hmd/Lefty1tm1Hmd
Nodaltm1Rob/Nodal+
involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * CD-1 		abnormal developmental patterning J:81339
abnormal embryo development J:81339
abnormal embryonic tissue morphology J:81339
abnormal embryonic-extraembryonic boundary morphology J:81339
Cer1tm1Bhr/Cer1tm1Bhr
Lefty1tm1Sla/Lefty1tm1Sla
involves: 129S7/SvEvBrd * CD-1 		abnormal embryonic epiblast morphology J:81339
abnormal lateral plate mesoderm morphology J:81339
abnormal paraxial mesoderm morphology J:81339
abnormal primitive streak formation J:81339
abnormal primitive streak morphology J:81339
absent somites J:81339
embryonic lethality during organogenesis, incomplete penetrance J:81339
embryonic-extraembryonic boundary constriction J:81339
Cer1tm1Bhr/Cer1tm1Bhr
Lefty1tm1Sla/Lefty1tm1Sla
Nodaltm1Rob/Nodal+
involves: 129S/SvEv * 129S7/SvEvBrd * CD-1 		abnormal developmental patterning J:81339
abnormal embryo development J:81339
abnormal embryonic tissue morphology J:81339
abnormal embryonic-extraembryonic boundary morphology J:81339
Lefty1tm1Hmd/Lefty1tm1Hmd
Shisa2tm1Sia/Shisa2tm1Sia
involves: 129P2/OlaHsd * C57BL/6 * CBA 		normal nervous system phenotype J:122557
Nodaltm1Hmd/Nodal+
Tg(Rr443-Lefty1,-lacZ)36Hmd/0
either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6N) or (involves: 129S1/Sv * 129T2/SvEms * 129X1/SvJ) 		abnormal cardiac outflow tract development J:82703
abnormal digestive system development J:82703
abnormal left-right axis patterning J:82703
abnormal liver morphology J:82703
dextrocardia J:82703
right atrial isomerism J:82703
right pulmonary isomerism J:82703
right-sided isomerism J:82703
small spleen J:82703
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory