Gucy2c Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gucy2c
guanylate cyclase 2c
MGI:106903

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gucy2c^tm1Gar/Gucy2c^tm1Gar B6.129S6-Gucy2c^tm1Gar	cardiac hypertrophy	J:178241
	hepatic steatosis	J:178241
	impaired glucose tolerance	J:178241
	increased body weight	J:178241
	increased circulating insulin level	J:178241
	increased circulating leptin level	J:178241
	increased compensatory feeding amount	J:178241
	increased heart weight	J:178241
	increased liver triglyceride level	J:178241
	increased subcutaneous adipose tissue amount	J:178241
	increased total body fat amount	J:178241
	polyphagia	J:178241
Gucy2c^tm1Gar/Gucy2c^tm1Gar either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6J)	decreased susceptibility to bacterial infection	J:43046
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:43046
	diarrhea	J:43046
Gucy2c^tm1Gian/Gucy2c^tm1Gian involves: 129P2/OlaHsd * Black Swiss	decreased susceptibility to infection	J:43682

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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