Myo1e Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myo1e
myosin IE
MGI:106621

33 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myo1e^{Gt(ROSA)74Sor}/Myo1e^{Gt(ROSA)74Sor} involves: 129S4/SvJaeSor	abnormal blood vessel morphology	J:117491
	anemia	J:117491
	decreased erythrocyte cell number	J:117491
	decreased hematocrit	J:117491
	decreased hemoglobin content	J:117491
	hemorrhage	J:117491
	polychromatophilia	J:117491
	prenatal lethality, incomplete penetrance	J:117491
	reticulocytosis	J:117491
Myo1e^tm1.1Flv/Myo1e^tm1.1Flv B6.129S6-Myo1e^tm1.1Flv	abnormal podocyte foot process morphology	J:188500
	abnormal renal glomerulus basement membrane morphology	J:188500
	albuminuria	J:188500
	glomerulosclerosis	J:188500
	increased renal glomerulus basement membrane thickness	J:188500
	podocyte foot process effacement	J:188500
	podocyte microvillus transformation	J:188500
	renal cast	J:188500
Myo1e^tm1.1Flv/Myo1e^tm1.1Flv involves: 129S6/SvEvTac	abnormal glomerular capillary morphology	J:159163
	abnormal podocyte foot process morphology	J:159163
	abnormal proximal convoluted tubule morphology	J:159163
	abnormal renal glomerular filtration rate	J:159163
	abnormal renal glomerulus morphology	J:159163
	abnormal urine homeostasis	J:159163
	albuminuria	J:159163
	enlarged kidney	J:159163
	expanded mesangial matrix	J:159163
	glomerulosclerosis	J:159163
	hematuria	J:159163
	hemoglobinuria	J:159163
	increased blood urea nitrogen level	J:159163
	increased kidney weight	J:159163
	increased renal glomerulus basement membrane thickness	J:159163
	increased urine protein level	J:159163
	leukocyturia	J:159163
	pale kidney	J:159163
	podocyte foot process effacement	J:159163
	proximal convoluted tubule brush border loss	J:159163
	renal cast	J:159163
	renal interstitial fibrosis	J:159163
Myo1e^tm1Flv/Myo1e^tm1.1Flv Tg(NPHS2-cre)295Lbh/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	albuminuria	J:188500
	glomerulosclerosis	J:188500
	renal cast	J:188500
Myo1e^tm1Flv/Myo1e^tm1Flv Tg(NPHS2-cre)295Lbh/0 involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal podocyte foot process morphology	J:188500
	abnormal renal glomerulus basement membrane morphology	J:188500
	albuminuria	J:188500
	glomerulosclerosis	J:188500
	increased renal glomerulus basement membrane thickness	J:188500
	podocyte foot process effacement	J:188500
	renal cast	J:188500

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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