Capza2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Capza2
capping actin protein of muscle Z-line subunit alpha 2
MGI:106222

41 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Capza2^em1Cya/Capza2⁺ C57BL/6N-Capza2^em1Cya	abnormal dendritic spine morphology	J:370017
	abnormal dentate gyrus neuron dendrite morphology	J:370017
	abnormal long-term spatial reference memory	J:370017
	abnormal neuron differentiation	J:370017
	abnormal neuron morphology	J:370017
	abnormal object recognition memory	J:370017
	decreased dendritic spine density	J:370017
	decreased dendritic spine number	J:370017
	decreased social investigation	J:370017
	decreased social novelty preference	J:370017
	impaired coordination	J:370017
	impaired spatial learning	J:370017
	impaired spatial working memory	J:370017
	increased anxiety-related response	J:370017
	increased dendritic spine density	J:370017
	increased dendritic spine length	J:370017
	increased dendritic spine number	J:370017
	increased locomotor activity	J:370017
Capza2^em1Yoch/Capza2⁺ C57BL/6-Capza2^em1Yoch	abnormal brain morphology	J:370017
	abnormal hippocampus neuron morphology	J:370017
	abnormal long-term spatial reference memory	J:370017
	abnormal neuron differentiation	J:370017
	abnormal object recognition memory	J:370017
	abnormal synapse morphology	J:370017
	decreased dendritic spine density	J:370017
	decreased dendritic spine number	J:370017
	decreased social investigation	J:370017
	decreased social novelty preference	J:370017
	hyperactivity	J:370017
	impaired coordination	J:370017
	impaired spatial learning	J:370017
	impaired spatial working memory	J:370017
	increased anxiety-related response	J:370017
	increased dendritic spine density	J:370017
Capza2^{tm1b(KOMP)Wtsi}/Capza2⁺ C57BL/6N-Capza2^{tm1b(KOMP)Wtsi}/Wtsi	increased circulating creatinine level	J:211773
	increased mean platelet volume	J:211773
Capza2^{tm1b(KOMP)Wtsi}/Capza2^{tm1b(KOMP)Wtsi} C57BL/6N-Capza2^{tm1b(KOMP)Wtsi}/Wtsi	abnormal ductus venosus valve morphology	J:239583
	abnormal hepatic vein connection	J:239583
	abnormal hypoglossal nerve topology	J:239583
	abnormal pulmonary valve cusp morphology	J:239583
	abnormal vertebral artery topology	J:239583
	absent hypoglossal nerve	J:239583
	bicuspid aortic valve	J:239583
	biliary cyst	J:239583
	blood in lymph vessels	J:239583
	dilated liver sinusoidal space	J:239583
	fusion of vertebral arches	J:239583
	increased trigeminal neuroma incidence	J:239583
	multiple persisting craniopharyngeal ducts	J:239583
	muscular ventricular septal defect	J:239583
	no abnormal phenotype detected	J:239583
	preweaning lethality, incomplete penetrance	J:211773
	thin hypoglossal nerve	J:239583

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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