Sle1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sle1
systemic lupus erythmatosus susceptibility 1
MGI:105969

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Sle1^NZM2410/Aeg/Sle1^NZM2410/Aeg Sle3^NZM2410/Aeg/Sle3^NZM2410/Aeg B6;NZM-Sle1^NZM2410/Aeg Sle2^NZM2410/Aeg Sle3^NZM2410/Aeg/LmoJ	abnormal marginal zone B cell physiology	J:138314
	increased marginal zone B cell number	J:138314
Sle1^NZW/Sle1^NZW Sles1^NZW/Sles1^NZW involves: C57BL/6 * NZW	abnormal T cell physiology	J:100678
	decreased susceptibility to systemic lupus erythematosus	J:100678
Sle1^NZW/Sle1^NZW Tg(Tnfsf13b)1Fma/0 involves: C57BL/6 * DBA/2J * NZW	glomerulonephritis	J:134128
	increased B cell number	J:134128
	increased IgG level	J:134128
	increased IgM level	J:134128
	increased marginal zone B cell number	J:134128
	increased susceptibility to systemic lupus erythematosus	J:134128

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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