Sle1 QTL Detail

Summary

• Symbol
  Sle1
• Name
  systemic lupus erythmatosus susceptibility 1

• Feature Type
  QTL
• IDs
  MGI:105969
  NCBI Gene: 112367

Location &
Maps

• Sequence Map
  Chr1:169038741-169038913 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 76.73 cM (cM position of peak correlated region/marker)
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from multigenic genotypes
  51 phenotype references
  

• All Mutations and Alleles
  3
• QTL
  3
• Find Mice (IMSR)
  2 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  112367

Other
Accession IDs

MGD-MRK-33648

References

• Summaries
  All 78

  Phenotypes 51
• Earliest
  J:25006 Morel L, et al., Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity. 1994 Jun;1(3):219-29
• Latest
  J:370564 Choi SC, et al., Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression. Sci Adv. 2024 Mar 29;10(13):eadi4310