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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hcfc1
host cell factor C1
MGI:105942
33 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Albtm1(cre/ERT2)Mtz/Alb+
Hcfc1tm1Lwh/Hcfc1+
involves: 129S2/SvPas * C57BL/6 		impaired liver regeneration J:231596
Hcfc1em1Poche/Y
C57BL/6J-Hcfc1em1Poche 		abnormal amino acid level J:317822
abnormal cranium morphology J:317822
abnormal enzyme/coenzyme activity J:317822
abnormal nasal bone morphology J:317822
abnormal ventricle myocardium morphology J:317822
belly spot J:317822
decreased body size J:317822
decreased digit pigmentation J:317822
decreased embryo size J:317822
decreased erythrocyte cell number J:317822
decreased hematocrit J:317822
decreased hemoglobin content J:317822
decreased tail pigmentation J:317822
increased circulating homocysteine level J:317822
increased circulating methylmalonic acid level J:317822
midface hypoplasia J:317822
postnatal lethality, incomplete penetrance J:317822
short face J:317822
small cranium J:317822
small frontal bone J:317822
small nasal bone J:317822
small parietal bone J:317822
thin cerebral cortex J:317822
upturned snout J:317822
Hcfc1em1Poche/Hcfc1em1Poche
C57BL/6J-Hcfc1em1Poche 		belly spot J:317822
Hcfc1tm1Lwh/Hcfc1+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA 		abnormal embryo morphology J:231596
abnormal extraembryonic tissue morphology J:231596
decreased body length J:231596
decreased cell proliferation J:231596
decreased embryo size J:231596
decreased lean body mass J:231596
embryonic lethality prior to organogenesis J:231596
embryonic lethality, complete penetrance J:231596
increased apoptosis J:231596
Hcfc1tm1Lwh/Y
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA 		decreased embryo size J:231596
embryonic lethality prior to organogenesis J:231596
embryonic lethality, complete penetrance J:231596
Hcfc1tm1Lwh/Hcfc1tm1Lwh
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: C57BL/6 * CBA 		abnormal embryo morphology J:231596
abnormal extraembryonic tissue morphology J:231596
decreased cell proliferation J:231596
decreased embryo size J:231596
embryonic lethality prior to organogenesis J:231596
embryonic lethality, complete penetrance J:231596
increased apoptosis J:231596
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory