Lair1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lair1
leukocyte-associated Ig-like receptor 1
MGI:105492

16 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lair1^tm1.1Jco/Lair1^tm1.1Jco involves: C57BL/6	decreased CD4-positive, alpha-beta T cell number	J:180203
	decreased CD8-positive, alpha-beta T cell number	J:180203
	decreased IgG1 level	J:180203
	decreased thymocyte number	J:180203
	increased activated T cell number	J:180203
	increased B cell number	J:180203
	increased CD4-positive, alpha-beta memory T cell number	J:180203
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:180203
	increased CD8-positive, alpha-beta memory T cell number	J:180203
	increased dendritic cell number	J:180203
	increased eosinophil cell number	J:180203
	increased marginal zone B cell number	J:180203
	thrombocytosis	J:180203
Lair1^tm1Jco/Lair1^tm1Jco B6.Cg-Lair1^tm1Jco	no abnormal phenotype detected	J:180203
Lair1^tm1Jco/Lair1^tm1Jco Tg(Cd4-cre)1Cwi/? involves: C57BL/6 * DBA/2	decreased IgG2a level	J:180203
	decreased IgG2b level	J:180203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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