Gcna Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gcna
germ cell nuclear acidic protein
MGI:105113

23 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gcna^tm1.1Dcp/Y Ddx4^{tm1.1(cre)Dcp}/Ddx4⁺ involves: C57BL/6 * C57BL/6N	abnormal chromosomal synapsis	J:284005
	abnormal DNA repair	J:284005
	abnormal male meiosis	J:284005
	abnormal sperm head morphology	J:284005
	absent chiasmata formation	J:284005
	chromosomal instability	J:284005
	male infertility	J:235710
	oligozoospermia	J:235710
	reduced male fertility	J:235710
Gcna^tm1.1Dcp/Y Dppa3^tm1(cre)Peli/Dppa3⁺ involves: 129S7/SvEvBrd * C57BL/6N	abnormal cell cycle	J:344952
	abnormal seminiferous tubule morphology	J:344952
	abnormal spermatogenesis	J:344952
	abnormal spermatogonia proliferation	J:344952
	abnormal testis morphology	J:344952
	normal cellular phenotype	J:344952
	decreased male germ cell number	J:344952
	decreased spermatogonia number	J:344952
	decreased testis weight	J:344952
	normal growth/size/body region phenotype	J:344952
	normal mortality/aging	J:344952
	oligozoospermia	J:344952
	testicular atrophy	J:344952
Gcna^tm1.1Dcp/Y Dppa3^tm1(cre)Peli/Dppa3⁺ Tg(Pou5f1-EGFP)2Mnn/0 involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N * CBA/CaJ	normal reproductive system phenotype	J:344952
Gcna^tm1.1Dcp/Gcna^tm1.1Dcp Ddx4^{tm1.1(cre)Dcp}/Ddx4⁺ involves: C57BL/6 * C57BL/6N	normal reproductive system phenotype	J:235710
Gcna^tm1.1Dcp/Gcna^tm1.1Dcp Dppa3^tm1(cre)Peli/Dppa3⁺ involves: 129S7/SvEvBrd * C57BL/6N	no abnormal phenotype detected	J:344952

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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