Ntn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ntn1
netrin 1
MGI:105088

28 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ntn1^{Gt(IRESBetageo)1Pgr}/Ntn1^{Gt(IRESBetageo)1Pgr} involves: 129/Sv * C57BL/6 * NMRI	abnormal brain commissure morphology	J:57002
	abnormal inner ear canal fusion	J:57002
	absent gastric milk in neonates	J:57002
	absent lateral semicircular canal	J:57002
	absent posterior semicircular canal	J:57002
	perinatal lethality, complete penetrance	J:57002
Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg B6.129P2-Ntn1^Gt(ST629)Byg	normal hearing/vestibular/ear phenotype	J:142510
	normal nervous system phenotype	J:109043
Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg involves: 129P2/OlaHsd	abnormal mammary gland development	J:109023
	normal nervous system phenotype	J:111725
	perinatal lethality, complete penetrance	J:109023
Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg involves: 129P2/OlaHsd * C57BL/6J	abnormal corticospinal tract morphology	J:80430
	abnormal pyramidal decussation morphology	J:80430
	abnormal spinal cord dorsal column morphology	J:80430
Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg involves: 129P2/OlaHsd * CD-1	abnormal anterior commissure morphology	J:37125
	abnormal brain commissure morphology	J:37125
	abnormal locomotor coordination	J:37125
	abnormal pontine nuclei morphology	J:37125
	abnormal righting response	J:37125
	absent corpus callosum	J:37125
	absent gastric milk in neonates	J:37125
	absent hippocampal commissure	J:37125
	postnatal lethality, complete penetrance	J:37125
Ntn1^tm1.2Good/Ntn1^tm1.2Good involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	abnormal palatal shelf fusion at midline	J:277765
	cleft secondary palate	J:277765
	coloboma	J:277765
Ntn1^tm1.2Tek/Ntn1^tm1.2Tek involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * SJL	abnormal axon guidance	J:227232
	abnormal dorsal spinal root morphology	J:227232
	abnormal spinal cord central canal morphology	J:227232
	abnormal spinal cord ependymal layer morphology	J:227232
	abnormal spinal cord ventral commissure morphology	J:227232
	lethality throughout fetal growth and development, complete penetrance	J:227232

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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