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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rbl2
RB transcriptional corepressor like 2
MGI:105085
33 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rbl2tm1b(EUCOMM)Hmgu/Rbl2+
C57BL/6N-Rbl2tm1b(EUCOMM)Hmgu/J
abnormal retina morphology J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
Rbl2tm1b(EUCOMM)Hmgu/Rbl2tm1b(EUCOMM)Hmgu
C57BL/6N-Rbl2tm1b(EUCOMM)Hmgu/J
preweaning lethality, incomplete penetrance J:211773
Rbl2tm1Mru/Rbl2tm1Mru
involves: 129S4/SvJae * BALB/cJ
abnormal cell proliferation J:50516
abnormal developmental patterning J:50516
abnormal floor plate morphology J:50516
abnormal heart morphology J:50516
abnormal myotome development J:50516
abnormal neuron differentiation J:50516
absent floor plate J:50516
absent hindlimb buds J:50516
absent notochord J:50516
normal cardiovascular system phenotype J:50516
normal cellular phenotype J:50516
decreased embryo size J:50516
normal embryo phenotype J:50516
embryonic growth arrest J:50516
embryonic lethality during organogenesis, complete penetrance J:50516
enlarged heart J:50516
failure of heart looping J:50516
failure of initiation of embryo turning J:50516
normal growth/size/body region phenotype J:50516
incomplete somite formation J:50516
increased apoptosis J:50516
increased neuron apoptosis J:50516
normal limbs/digits/tail phenotype J:50516
normal mortality/aging J:50516
normal muscle phenotype J:50516
normal nervous system phenotype J:50516
thin myocardium J:50516
Rbl2tm1Mru/Rbl2tm1Mru
involves: 129S4/SvJae * BALB/cJ * C57BL/6J
no abnormal phenotype detected J:50516
Rbl2tm1Tyj/Rbl2+
involves: 129S2/SvPas * C57BL/6
no abnormal phenotype detected J:34725
Rbl2tm1Tyj/Rbl2tm1Tyj
involves: 129S2/SvPas * C57BL/6
normal cellular phenotype J:34725
normal integument phenotype J:82802
no abnormal phenotype detected J:34725

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory