Satb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Satb1
special AT-rich sequence binding protein 1
MGI:105084

38 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Satb1^em1Zfa/Satb1^em1Zfa involves: C57BL/6	decreased common lymphocyte progenitor cell number	J:259392
Satb1^em1Zfa/Satb1^em1Zfa involves: C57BL/6	premature death	J:259392
Satb1^m1Anu/Satb1⁺ C57L/6JAnu-Satb1^m1Anu	abnormal CD4-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1⁺ C57L/6JAnu-Satb1^m1Anu	abnormal CD8-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1^m1Anu C57L/6JAnu-Satb1^m1Anu	abnormal CD4-positive, alpha beta T cell morphology	J:104190
Satb1^m1Anu/Satb1^m1Anu C57L/6JAnu-Satb1^m1Anu	abnormal CD8-positive, alpha beta T cell morphology	J:104190
Satb1^{tm1a(EUCOMM)Hmgu}/Satb1^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	abnormal brain interneuron morphology	J:196342
	normal nervous system phenotype	J:196342
	postnatal growth retardation	J:196342
	postnatal lethality, complete penetrance	J:196342
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1⁺ C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/Ics	abnormal auditory brainstem response	J:211773
	abnormal vitreous body morphology	J:211773
	increased circulating aspartate transaminase level	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1⁺ C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/J	abnormal bone structure	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
	increased exploration in new environment	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Satb1^{tm1b(EUCOMM)Hmgu}/Satb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Satb1^{tm1b(EUCOMM)Hmgu}/J	preweaning lethality, incomplete penetrance	J:211773
Satb1^tm1Kos/Satb1^tm1Kos involves: 129P2/OlaHsd * C57BL/6	abnormal T cell differentiation	J:61085
	abnormal T cell proliferation	J:61085
	arrested T cell differentiation	J:61085
	decreased body size	J:61085
	decreased thymocyte number	J:61085
	delayed eyelid opening	J:61085
	limb grasping	J:61085
	postnatal growth retardation	J:61085
	postnatal lethality, complete penetrance	J:61085
	small lymph nodes	J:61085
	small spleen	J:61085
	small thymus	J:61085
Satb1^tm2Kos/Satb1^tm2Kos Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6 * C57BL/10 * CBA/Ca	abnormal renal glomerulus morphology	J:252606
	absent regulatory T cells	J:252606
	decreased salivation	J:252606
	increased anti-nuclear antigen antibody level	J:252606
	increased autoantibody level	J:252606
	increased susceptibility to autoimmune disorder	J:252606
	increased urine protein level	J:252606
	kidney inflammation	J:252606
	pancreas inflammation	J:252606
	premature death	J:252606
	salivary gland degeneration	J:252606
	salivary gland inflammation	J:252606

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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