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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
MGI:104855
14 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atp6v0a2tm1Kdb/Atp6v0a2tm1Kdb
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/6 * C57BL/10 * CBA/Ca 		abnormal CD8-positive, alpha-beta cytotoxic T cell morphology J:274048
decreased alpha-beta T cell number J:274048
decreased CD4-positive, alpha-beta T cell number J:274048
decreased T cell number J:274048
decreased tumor latency J:274048
increased incidence of induced tumors J:274048
increased metastatic potential J:274048
Atp6v0a2tm1Kdb/Atp6v0a2tm1Kdb
Tg(MMTV-cre)4Mam/0
involves: 129 * C57BL/6 * FVB 		abnormal branching of the mammary ductal tree J:274047
abnormal lactation J:274047
abnormal mammary duct terminal end bud morphology J:274047
abnormal mammary gland development J:274047
abnormal mammary gland duct morphology J:274047
abnormal mammary gland epithelium morphology J:274047
impaired mammary gland growth during pregnancy J:274047
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory