Meis1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Meis1
Meis homeobox 1
MGI:104717

36 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Meis1^{tm1b(EUCOMM)Hmgu}/Meis1⁺ C57BL/6N-Meis1^{tm1b(EUCOMM)Hmgu}/J	decreased prepulse inhibition	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
	increased startle reflex	J:211773
Meis1^{tm1b(EUCOMM)Hmgu}/Meis1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Meis1^{tm1b(EUCOMM)Hmgu}/J	preweaning lethality, complete penetrance	J:211773
Meis1^tm1Mtor/Meis1^tm1Mtor involves: CD-1	abnormal blood vessel morphology	J:98307
	abnormal megakaryocyte progenitor cell morphology	J:98307
	absent common myeloid progenitor cells	J:98307
	absent platelets	J:98307
	embryonic lethality during organogenesis, incomplete penetrance	J:98307
	hemorrhage	J:98307
	impaired hematopoiesis	J:98307
	lethality throughout fetal growth and development, complete penetrance	J:98307
	liver hypoplasia	J:98307
	pallor	J:98307
Meis1^tm1Mtor/Meis1^tm1Mtor Not Specified	hemorrhage	J:217599
	microphthalmia	J:217599
	pallor	J:217599
Meis1^tm1Ngc/Meis1^tm1Ngc involves: 129 * C57BL/6NCr	abnormal angiogenesis	J:87890
	abnormal brain morphology	J:87890
	abnormal capillary branching pattern	J:87890
	abnormal capillary morphology	J:87890
	abnormal heart morphology	J:87890
	abnormal kidney morphology	J:87890
	abnormal liver morphology	J:87890
	abnormal lung morphology	J:87890
	abnormal retina morphology	J:87890
	abnormal vascular branching morphogenesis	J:87890
	absent megakaryocytes	J:87890
	decreased common myeloid progenitor cell number	J:87890
	hemorrhage	J:87890
	lethality throughout fetal growth and development, complete penetrance	J:87890
	normal limbs/digits/tail phenotype	J:87890
	small lens	J:87890
Meis1^tm1Ngc/Meis1^tm1Ngc involves: 129S1/SvImJ	embryonic lethality during organogenesis, complete penetrance	J:87890
Meis1^tm1Ngc/Meis1^tm1Ngc involves: 129S1/SvImJ	hemorrhage	J:87890
Meis1^tm2.1Mtor/Meis1^tm2.1Mtor involves: 129S1/Sv * 129X1/SvJ	absent megakaryocytes	J:217599
	hemorrhage	J:217599
	microphthalmia	J:217599
	pallor	J:217599
	ventricular septal defect	J:217599
Meis1^tm2Ngc/Meis1^tm2Ngc Tg(Tal1-cre/ERT)42-056Jrg/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6J	abnormal bone marrow cell morphology/development	J:192126
	abnormal hematopoietic stem cell physiology	J:192126
	decreased common myeloid progenitor cell number	J:192126
	increased hematopoietic stem cell number	J:192126
	oxidative stress	J:192126
Meis1^{tm3.1(cre/ERT2)Mtor}/Meis1^{tm3.1(cre/ERT2)Mtor} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	hemorrhage	J:217599
	microphthalmia	J:217599
	pallor	J:217599

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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