Tgfbr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgfbr3
transforming growth factor, beta receptor III
MGI:104637

43 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tgfbr3^em1(IMPC)Mbp/Tgfbr3⁺ C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal placenta morphology	J:211773
	enlarged kidney	J:211773
	microphthalmia	J:211773
Tgfbr3^em1(IMPC)Mbp/Tgfbr3^em1(IMPC)Mbp C57BL/6N-Tgfbr3^em1(IMPC)Mbp/MbpMmucd	abnormal blood vessel morphology	J:211773
	abnormal liver size	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	hemorrhage	J:211773
	pale liver	J:211773
	preweaning lethality, complete penetrance	J:211773
Tgfbr3^tm1.1Jba/Tgfbr3^tm1.1Jba involves: 129S6/SvEvTac	abnormal palatal shelf bone ossification	J:218259
	abnormal palatal shelf fusion at midline	J:218259
	abnormal palate development	J:218259
	abnormal vasculogenesis	J:218259
	decreased palatal shelf size	J:218259
	decreased tongue size	J:218259
	failure of palatal shelf elevation	J:218259
	lethality throughout fetal growth and development, complete penetrance	J:218259
Tgfbr3^tm1.1Jba/Tgfbr3^tm1.1Jba involves: 129S6/SvEvTac * C57BL/6	abnormal epicardium morphology	J:141344
	abnormal truncus arteriosus septation	J:141344
	abnormal vasculogenesis	J:141344
	lethality throughout fetal growth and development, complete penetrance	J:141344
	thin myocardium	J:141344
	transposition of great arteries	J:141344
Tgfbr3^tm1Stv/Tgfbr3^tm1Stv involves: 129/Sv * C57BL/6	abnormal axial skeleton morphology	J:83727
	abnormal definitive hematopoiesis	J:83727
	abnormal femur morphology	J:83727
	abnormal fertility/fecundity	J:83727
	abnormal fetal cardiomyocyte proliferation	J:83727
	abnormal interventricular septum muscular part morphology	J:83727
	abnormal liver development	J:83727
	abnormal skeleton development	J:83727
	abnormal spleen morphology	J:83727
	abnormal sternum morphology	J:83727
	abnormal trochanter morphology	J:83727
	absent deltoid tuberosity	J:83727
	decreased myocardial fiber number	J:83727
	decreased spleen white pulp amount	J:83727
	lethality throughout fetal growth and development, incomplete penetrance	J:83727
	muscular ventricular septal defect	J:83727
	rib fusion	J:83727
	trabecula carnea hypoplasia	J:83727
	ventricle myocardium hypoplasia	J:83727

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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