Eps15 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eps15
epidermal growth factor receptor pathway substrate 15
MGI:104583

17 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eps15^{tm1a(KOMP)Wtsi}/Eps15^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Eps15^{tm1a(KOMP)Wtsi}/Wtsi	decreased leukocyte cell number	J:165965
	decreased mean corpuscular hemoglobin	J:165965
	increased body weight	J:165965
	increased circulating HDL cholesterol level	J:175295
	increased circulating LDL cholesterol level	J:175295
Eps15^{tm1a(KOMP)Wtsi}/Eps15^{tm1a(KOMP)Wtsi} involves: C57BL/6 * C57BL/6N	decreased mean corpuscular hemoglobin	J:213427
	decreased mean corpuscular hemoglobin concentration	J:213427
	dermatitis	J:213427
Eps15^tm1Noff/Eps15^tm1Noff B6.129-Eps15^tm1Noff	abnormal spleen B cell follicle morphology	J:195689
	abnormal spleen marginal zone morphology	J:195689
	abnormal spleen white pulp morphology	J:195689
	decreased B cell number	J:195689
	decreased leukocyte cell number	J:195689
	decreased lymphocyte cell number	J:195689
	normal immune system phenotype	J:195689
	increased marginal zone B cell number	J:195689
	normal nervous system phenotype	J:195689
Eps15^tm1Noff/Eps15^tm1Noff involves: 129 * C57BL/6	abnormal marginal zone B cell morphology	J:195689
	increased marginal zone B cell number	J:195689
	increased transitional stage T1 B cell number	J:195689

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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