Myo7a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Myo7a
myosin VIIA
MGI:104510

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdh23^v-2J/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	absent pinna reflex	J:108877
Cdh23^v-2J/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	increased susceptibility to age-related hearing loss	J:108877
Cdh23^v-2J/Cdh23⁺ Myo7a^sh1-8J/Myo7a⁺ B6.Cg-Myo7a^sh1-8J Cdh23^v-2J	increased or absent threshold for auditory brainstem response	J:183898
Cdh23^v/Cdh23⁺ Myo7a^sh1/Myo7a⁺ involves: BALB	deafness	J:13130
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ involves: BALB/cRl * 47BS/Rl * CBA/Ca	abnormal cochlear nerve compound action potential	J:134369
	abnormal outer hair cell stereociliary bundle morphology	J:134369
	decreased cochlear outer hair cell number	J:134369
	decreased outer hair cell stereocilia number	J:134369
	normal hearing/vestibular/ear phenotype	J:134369
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	absent pinna reflex	J:108877
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a⁺ mixed	increased susceptibility to age-related hearing loss	J:108877
Cdh23^v/Cdh23⁺ Myo7a^4626SB/Myo7a^4626SB mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a⁺ mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a^4626SB involves: 47BS/Rl * CBA/Ca	abnormal eye electrophysiology	J:109546
	normal vision/eye phenotype	J:109546
Cdh23^v/Cdh23^v Myo7a^4626SB/Myo7a^4626SB mixed	abnormal outer hair cell stereociliary bundle morphology	J:108877
Hprt1^tm2Brd/Hprt1⁺ Myo7a^4626SB/Myo7a^4626SB involves: 129S7/SvEvBrd * BALB/cRl * C3H * C57BL/6J * CBA/Ca	normal hearing/vestibular/ear phenotype	J:132633
Hprt1^tm3Brd/Hprt1⁺ Myo7a^4626SB/Myo7a^4626SB involves: 129S7/SvEvBrd * BALB/cRl * C3H * C57BL/6J * CBA/Ca	normal hearing/vestibular/ear phenotype	J:132633
Myo7a^sh1-8J/Myo7a⁺ Pcdh15^av-3J/Pcdh15⁺ B6.Cg-Myo7a^sh1-8J Pcdh15^av-3J	increased or absent threshold for auditory brainstem response	J:183898
Myo7a^sh1-8J/Myo7a⁺ Ush1g^js/Ush1g⁺ B6.Cg-Myo7a^sh1-8J Ush1g^js	increased or absent threshold for auditory brainstem response	J:183898

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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