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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Myo7a
myosin VIIA
MGI:104510
86 phenotypes from 21 alleles in 23 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Myo7a26SB/Myo7a26SB
involves: BALB/cRl
abnormal hair cell morphology J:49926
abnormal hearing physiology J:49926
Myo7a816SB/Myo7a816SB
involves: BALB/cRl
abnormal hair cell morphology J:49926
abnormal hearing physiology J:49926
Myo7a816SB/Myo7a816SB
involves: BALB/cRl * 47BS/Rl
abnormal auditory summating potential J:46373
abnormal cochlear hair cell stereociliary bundle morphology J:46373
abnormal orientation of cochlear hair cell stereociliary bundles J:46373
absent cochlear microphonics J:46373
Myo7a3336SB/Myo7a3336SB
involves: BALB/cRl
abnormal hair cell morphology J:49926
abnormal hearing physiology J:49926
Myo7a4494SB/Myo7a4494SB
involves: BALB/cRl
abnormal hair cell morphology J:49926
abnormal hearing physiology J:49926
Myo7a4626SB/Myo7a+
involves: BALB/cRl * 47BS/Rl * CBA/Ca
abnormal cochlear nerve compound action potential J:134369
abnormal outer hair cell stereociliary bundle morphology J:134369
decreased cochlear outer hair cell number J:134369
decreased outer hair cell stereocilia number J:134369
impaired hearing J:134369
increased susceptibility to age-related hearing loss J:134369
Myo7a4626SB/Myo7a4626SB
involves: 129S7/SvEvBrd * BALB/cRl * C3H * C57BL/6J * CBA/Ca
abnormal cochlear hair cell stereociliary bundle morphology J:132633
Myo7a4626SB/Myo7a4626SB
involves: BALB/cRl
abnormal cochlear hair cell inter-stereocilial links morphology J:135991
abnormal cochlear outer hair cell morphology J:158897
abnormal inner hair cell stereociliary bundle morphology J:135991
abnormal orientation of cochlear hair cell stereociliary bundles J:135991
abnormal outer hair cell stereociliary bundle morphology J:135991, J:158897
absent cochlear hair bundle ankle links J:135991
cochlear outer hair cell degeneration J:135991
short cochlear outer hair cells J:135991
Myo7a4626SB/Myo7a4626SB
involves: BALB/cRl * 47BS/Rl * C3Hf/Rl * C57BL/10Rl * CBA/Ca
abnormal outer hair cell stereociliary bundle morphology J:108877
Myo7admbo2/Myo7admbo2
involves: C57BL/6J
abnormal cochlear hair cell stereociliary bundle morphology J:195666
abnormal inner hair cell stereociliary bundle morphology J:195666
abnormal orientation of outer hair cell stereociliary bundles J:195666
abnormal vestibular hair cell stereociliary bundle morphology J:195666
decreased inner hair cell stereocilia number J:195666
normal hearing/vestibular/ear phenotype J:195666
impaired hearing J:195666
increased or absent threshold for auditory brainstem response J:195666
Myo7aewaso/Myo7a+
involves: C57BL/6J
increased or absent threshold for auditory brainstem response J:195666
Myo7aewaso/Myo7aewaso
involves: C57BL/6J
abnormal cochlear basement membrane morphology J:195666
abnormal cochlear outer hair cell morphology J:195666
abnormal inner hair cell stereociliary bundle morphology J:195666
abnormal orientation of inner hair cell stereociliary bundles J:195666
abnormal vestibular hair cell stereociliary bundle morphology J:195666
circling J:195666
cochlear hair cell degeneration J:195666
decreased inner hair cell stereocilia number J:195666
decreased outer hair cell stereocilia number J:195666
decreased vestibular hair cell stereocilia number J:195666
fused inner hair cell stereocilia J:195666
normal hearing/vestibular/ear phenotype J:195666
impaired hearing J:195666
increased or absent threshold for auditory brainstem response J:195666
trunk curl J:195666
Myo7aHdb/Myo7a+
C3HeB/FeJ-Myo7aHdb/Ieg
abnormal inner hair cell stereociliary bundle morphology J:93998
abnormal outer hair cell stereociliary bundle morphology J:93998
abnormal vestibular hair cell stereociliary bundle morphology J:93998
fused inner hair cell stereocilia J:93998
head bobbing J:93998
hyperactivity J:93998
increased cochlear nerve compound action potential J:93998
Myo7aHdb/Myo7a4626SB
involves: BALB/c * 47BS/Rl * C3HeB/FeJ * CBA/Ca
abnormal inner hair cell stereociliary bundle morphology J:93998
abnormal outer hair cell stereociliary bundle morphology J:93998
fused inner hair cell stereocilia J:93998
Myo7aHdb/Myo7aHdb
C3HeB/FeJ-Myo7aHdb/Ieg
abnormal inner hair cell stereociliary bundle morphology J:93998
abnormal outer hair cell stereociliary bundle morphology J:93998
decreased inner hair cell stereocilia number J:93998
decreased outer hair cell stereocilia number J:93998
fused inner hair cell stereocilia J:93998
head bobbing J:93998
hyperactivity J:93998
increased cochlear nerve compound action potential J:93998
Myo7am1Btlr/Myo7am1Btlr
C57BL/6J-Myo7am1Btlr
circling J:213050
head tossing J:213050
hyperactivity J:213050
Myo7ampc142H/Myo7ampc142H
involves: BALB/c * C3H/HeH * C57BL/6J
abnormal inner ear vestibule morphology J:234901
deafness J:234901
Myo7apolka/Myo7apolka
involves: C57BL/6J
abnormal cochlear hair cell stereociliary bundle morphology J:157102
abnormal retina pigment epithelium morphology J:157102
absent distortion product otoacoustic emissions J:157102
circling J:119820
decreased startle reflex J:119820
impaired swimming J:119820
increased or absent threshold for auditory brainstem response J:119820
short cochlear hair cell stereocilia J:157102
Myo7ash1-1R/Myo7ash1-1R
involves: D7R75M
impaired balance J:81149
Myo7ash1-6J/Myo7ash1-6J
involves: C57BLKS/J
abnormal gait J:17340
deafness J:17340
decreased body size J:17340
head tossing J:17340
impaired swimming J:17340
male infertility J:17340
retropulsion J:17340
Myo7ash1-7J/Myo7ash1-7J
STOCK Myo7ash1-7J/J
circling J:91063
deafness J:91063
head shaking J:91063
head tilt J:91063
Myo7ash1-7J/Myo7ash1-8J
B6.Cg-Myo7ash1-7J Myo7ash1-8J
absent startle reflex J:183898
circling J:183898
Myo7ash1-8J/Myo7a+
B6.Cg-Myo7ash1-8J/J
impaired hearing J:183898
Myo7ash1-8J/Myo7ash1-8J
B6.Cg-Myo7ash1-8J/J
abnormal cochlear hair cell stereociliary bundle morphology J:183898
abnormal parental behavior J:77937
abnormal vestibular hair cell stereociliary bundle morphology J:183898
circling J:77937, J:183898
head bobbing J:77937
increased or absent threshold for auditory brainstem response J:183898
normal pigmentation phenotype J:141035
Myo7ash1-9J/Myo7ash1-9J
involves: C3.MRL-Faslpr/J
circling J:49039
deafness J:49039
Myo7ash1-11J/Myo7ash1-11J
129.B6-Myo7ash1-11J
abnormal retina rod cell morphology J:181430
retina rod cell degeneration J:181430
Myo7ash1-11J/Myo7ash1-11J
C57BL/6J-Myo7ash1-11J/J
circling J:82238
head tilt J:82238
Myo7ash1-13J/Myo7ash1-13J
C.Cg-Myo7ash1-13J/GrsrJ
abnormal gait J:209272
abnormal head movements J:209272
head bobbing J:209272
head shaking J:209272
head tossing J:209272
retropulsion J:209272
straub tail J:209272
Myo7ash1/Myo7ash1
involves: BALB
abnormal behavior J:15554
abnormal cochlear hair cell morphology J:14846
abnormal cochlear OHC efferent innervation pattern J:28477
abnormal ear physiology J:14858
abnormal organ of Corti morphology J:14846, J:28477
absent pinna reflex J:14858
circling J:15554, J:93998
cochlear ganglion degeneration J:13130, J:14846, J:14858, J:28477
cochlear hair cell degeneration J:13130, J:14858, J:93998
deafness J:14858, J:15554, J:93998
gliosis J:14891
head tossing J:93998
hyperactivity J:15554, J:93998
impaired swimming J:13130
increased anxiety-related response J:15554
increased fluid intake J:15554
increased food intake J:15554
jerky movement J:15554
reduced male fertility J:15554
slow postnatal weight gain J:15554
stria vascularis degeneration J:14858
vestibular ganglion hypoplasia J:13130
vestibular saccular macula degeneration J:13130
Myo7ash1/Myo7ash1
SH1/LeJ
absent linear vestibular evoked potential J:116914
circling J:116914
impaired swimming J:116914
Myo7atm1a(EUCOMM)Wtsi/Myo7atm1a(EUCOMM)Wtsi
C57BL/6N-Myo7atm1a(EUCOMM)Wtsi/Wtsi
absent pinna reflex J:211773
impaired righting response J:211773
increased blood urea nitrogen level J:211773
increased circulating sodium level J:211773
persistence of hyaloid vascular system J:211773
stereotypic behavior J:211773
trunk curl J:211773
Myo7atm1b(EUCOMM)Wtsi/Myo7a+
B6J.Cg-Myo7atm1b(EUCOMM)Wtsi
abnormal electroretinogram waveform feature J:283233
cochlear ganglion degeneration J:283233
cochlear outer hair cell degeneration J:283233
decreased a-wave amplitude J:283233
decreased b-wave amplitude J:283233
increased or absent threshold for auditory brainstem response J:283233
sensorineural hearing loss J:283233
Myo7atm1b(EUCOMM)Wtsi/Myo7atm1b(EUCOMM)Wtsi
B6J.Cg-Myo7atm1b(EUCOMM)Wtsi
abnormal electroretinogram waveform feature J:283233
cochlear degeneration J:283233
cochlear ganglion degeneration J:283233
cochlear hair cell degeneration J:283233
deafness J:283233
decreased a-wave amplitude J:283233
decreased b-wave amplitude J:283233
head tilt J:283233
hyperactivity J:283233
impaired pupillary reflex J:283233
increased or absent threshold for auditory brainstem response J:283233
sensorineural hearing loss J:283233
spinning J:283233
thin stria vascularis J:283233

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory