Rhbdf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rhbdf1
rhomboid 5 homolog 1
MGI:104328

36 phenotypes from 8 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs}/Rhbdf1⁺ involves: 129P2/OlaHsd * C57BL/6 * CBA	anisopoikilocytosis	J:117887
Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs}/Rhbdf1/Hba^{tm1(RHBDF1/HBA)Ajhs} involves: 129P2/OlaHsd * C57BL/6 * CBA	anisopoikilocytosis	J:117887
	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	microcytosis	J:117887
	neonatal lethality, incomplete penetrance	J:117887
	prenatal lethality, incomplete penetrance	J:117887
	reticulocytosis	J:117887
Rhbdf1/Hba^{tm1.1(RHBDF1/HBA)Ajhs}/Rhbdf1/Hba^{tm1.1(RHBDF1/HBA)Ajhs} involves: 129P2/OlaHsd * C57BL/6 * CBA	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	reticulocytosis	J:117887
Rhbdf1/Hba^tm2.1Ajhs/Rhbdf1⁺ involves: 129P2/OlaHsd * C57BL/6	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
Rhbdf1/Hba^tm2Ajhs/Rhbdf1⁺ involves: 129P2/OlaHsd * C57BL/6	anisopoikilocytosis	J:117887
	decreased hemoglobin content	J:117887
	decreased mean corpuscular hemoglobin	J:117887
	decreased mean corpuscular volume	J:117887
	microcytosis	J:117887
Rhbdf1/Hba^tm2Ajhs/Rhbdf1/Hba^tm2Ajhs involves: 129P2/OlaHsd * C57BL/6	anemia	J:117887
	decreased embryo size	J:117887
	embryonic lethality during organogenesis, complete penetrance	J:117887
	pallor	J:117887
Rhbdf1^em1Mvw/Rhbdf1^em1Mvw C57BL/6J-Rhbdf1^em1Mvw/Mvw	no abnormal phenotype detected	J:291556
Rhbdf1^{tm1.1(KOMP)Vlcg}/Rhbdf1⁺ C57BL/6N-Rhbdf1^{tm1.1(KOMP)Vlcg}/J	decreased bone mineral density	J:211773
	increased grip strength	J:211773
Rhbdf1^{tm1.1(KOMP)Vlcg}/Rhbdf1^{tm1.1(KOMP)Vlcg} C57BL/6N-Rhbdf1^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, incomplete penetrance	J:211773
Rhbdf1^tm1.1Mfm/Rhbdf1^tm1.1Mfm B6.129S-Rhbdf1^tm1.1Mfm	ataxia	J:203951
	impaired coordination	J:203951
	postnatal lethality, complete penetrance	J:203951
Rhbdf1^tm1.1Mfm/Rhbdf1^tm1.1Mfm involves: 129S/SvEv * 129S6/SvEvTac	decreased body weight	J:203951
	impaired coordination	J:203951
	increased eating frequency	J:203951
	intracerebral hemorrhage	J:203951
	premature death	J:203951
	weight loss	J:203951
Rhbdf1^tm1.1Mfm/Rhbdf1^tm1.1Mfm involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6J	abnormal cardiac thrombosis	J:203951
	abnormal heart morphology	J:203951
	abnormal pancreatic acinus morphology	J:203951
	absent pancreatic acinar cell zymogen granule	J:203951
	decreased body weight	J:203951
	decreased bone marrow cell number	J:203951
	decreased white adipose tissue amount	J:203951
	normal hematopoietic system phenotype	J:203951
	pancreatic acinar hypoplasia	J:203951
	postnatal lethality, incomplete penetrance	J:203951
	premature death	J:203951
	slow postnatal weight gain	J:203951
	small spleen	J:203951
	small thymus	J:203951
Rhbdf1^{tm1b(EUCOMM)Wtsi}/Rhbdf1^{tm1b(EUCOMM)Wtsi} involves: C57BL/6N * FVB/N	no abnormal phenotype detected	J:221411

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