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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rhbdf1
rhomboid 5 homolog 1
MGI:104328
36 phenotypes from 8 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs/Rhbdf1+
involves: 129P2/OlaHsd * C57BL/6 * CBA
anisopoikilocytosis J:117887
Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs/Rhbdf1/Hbatm1(RHBDF1/HBA)Ajhs
involves: 129P2/OlaHsd * C57BL/6 * CBA
anisopoikilocytosis J:117887
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
microcytosis J:117887
neonatal lethality, incomplete penetrance J:117887
prenatal lethality, incomplete penetrance J:117887
reticulocytosis J:117887
Rhbdf1/Hbatm1.1(RHBDF1/HBA)Ajhs/Rhbdf1/Hbatm1.1(RHBDF1/HBA)Ajhs
involves: 129P2/OlaHsd * C57BL/6 * CBA
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
reticulocytosis J:117887
Rhbdf1/Hbatm2.1Ajhs/Rhbdf1+
involves: 129P2/OlaHsd * C57BL/6
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
Rhbdf1/Hbatm2Ajhs/Rhbdf1+
involves: 129P2/OlaHsd * C57BL/6
anisopoikilocytosis J:117887
decreased hemoglobin content J:117887
decreased mean corpuscular hemoglobin J:117887
decreased mean corpuscular volume J:117887
microcytosis J:117887
Rhbdf1/Hbatm2Ajhs/Rhbdf1/Hbatm2Ajhs
involves: 129P2/OlaHsd * C57BL/6
anemia J:117887
decreased embryo size J:117887
embryonic lethality during organogenesis, complete penetrance J:117887
pallor J:117887
Rhbdf1em1Mvw/Rhbdf1em1Mvw
C57BL/6J-Rhbdf1em1Mvw/Mvw
no abnormal phenotype detected J:291556
Rhbdf1tm1.1(KOMP)Vlcg/Rhbdf1+
C57BL/6N-Rhbdf1tm1.1(KOMP)Vlcg/J
decreased bone mineral density J:211773
increased grip strength J:211773
Rhbdf1tm1.1(KOMP)Vlcg/Rhbdf1tm1.1(KOMP)Vlcg
C57BL/6N-Rhbdf1tm1.1(KOMP)Vlcg/J
preweaning lethality, incomplete penetrance J:211773
Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm
B6.129S-Rhbdf1tm1.1Mfm
ataxia J:203951
impaired coordination J:203951
postnatal lethality, complete penetrance J:203951
Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm
involves: 129S/SvEv * 129S6/SvEvTac
decreased body weight J:203951
impaired coordination J:203951
increased eating frequency J:203951
intracerebral hemorrhage J:203951
premature death J:203951
weight loss J:203951
Rhbdf1tm1.1Mfm/Rhbdf1tm1.1Mfm
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6J
abnormal cardiac thrombosis J:203951
abnormal heart morphology J:203951
abnormal pancreatic acinus morphology J:203951
absent pancreatic acinar cell zymogen granule J:203951
decreased body weight J:203951
decreased bone marrow cell number J:203951
decreased white adipose tissue amount J:203951
normal hematopoietic system phenotype J:203951
pancreatic acinar hypoplasia J:203951
postnatal lethality, incomplete penetrance J:203951
premature death J:203951
slow postnatal weight gain J:203951
small spleen J:203951
small thymus J:203951
Rhbdf1tm1b(EUCOMM)Wtsi/Rhbdf1tm1b(EUCOMM)Wtsi
involves: C57BL/6N * FVB/N
no abnormal phenotype detected J:221411

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory