Tiam1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tiam1
T cell lymphoma invasion and metastasis 1
MGI:103306

12 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tiam1^{Gt(CSJ260)Byg}/Tiam1^{Gt(CSJ260)Byg} involves: 129P2/OlaHsd	abnormal diencephalon morphology	J:188067
	abnormal forebrain morphology	J:188067
	anencephaly	J:188067
	exencephaly	J:188067
Tiam1^{tm1b(EUCOMM)Hmgu}/Tiam1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tiam1^{tm1b(EUCOMM)Hmgu}/Ics	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	increased cornea thickness	J:211773
Tiam1^tm1Jgc/Tiam1⁺ involves: 129P2/OlaHsd * FVB	decreased incidence of tumors by chemical induction	J:77148
Tiam1^tm1Jgc/Tiam1^tm1Jgc involves: 129P2/OlaHsd * FVB	abnormal apoptosis	J:77148
	decreased cell proliferation	J:77148
	decreased incidence of tumors by chemical induction	J:77148
	increased malignant tumor incidence	J:77148
	increased squamous cell carcinoma incidence	J:77148

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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