Cdc25a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc25a
cell division cycle 25A
MGI:103198

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc25a^tm1Hpw/Cdc25a^tm1.1Hpw Cdc25b^tm1Pjd/Cdc25b^tm1Pjd Cdc25c^tm1Hpw/Cdc25c^tm1Hpw Gt(ROSA)26Sor^{tm1(cre/ERT)Brn}/Gt(ROSA)26Sor⁺ involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	abnormal small intestinal villus morphology	J:145768
	abnormal small intestine crypts of Lieberkuhn morphology	J:145768
	decreased small intestinal villus height	J:145768
	decreased small intestine length	J:145768
	premature death	J:145768
	weight loss	J:145768
Cdc25a^tm1Hpw/Cdc25a^tm1.1Hpw Cdc25b^tm1Pjd/Cdc25b^tm1Pjd Cdc25c^tm1Hpw/Cdc25c^tm1Hpw Tg(Vil1-cre/ERT2)23Syr/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal enterocyte differentiation	J:169457
	abnormal large intestine morphology	J:169457
	abnormal small intestinal crypt cell proliferation	J:169457
	abnormal small intestine crypts of Lieberkuhn morphology	J:169457
	abnormal small intestine morphology	J:169457
	decreased body weight	J:169457
	decreased small intestinal villus size	J:169457
	increased enterocyte apoptosis	J:169457
	postnatal lethality, incomplete penetrance	J:169457
Cdc25a^tm1Hpw/Cdc25a^tm1.1Hpw Cdc25b^tm1Pjd/Cdc25b^tm1Pjd Tg(Vil1-cre/ERT2)23Syr/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	abnormal enterocyte differentiation	J:169457
	abnormal large intestine morphology	J:169457
	abnormal small intestinal crypt cell proliferation	J:169457
	abnormal small intestine crypts of Lieberkuhn morphology	J:169457
	abnormal small intestine morphology	J:169457
	decreased body weight	J:169457
	decreased small intestinal villus size	J:169457
	increased enterocyte apoptosis	J:169457
	postnatal lethality, incomplete penetrance	J:169457
Cdc25a^tm1Hpw/Cdc25a^tm1.1Hpw Cdc25c^tm1Hpw/Cdc25c^tm1Hpw Tg(Vil1-cre/ERT2)23Syr/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	normal digestive/alimentary phenotype	J:169457
	normal growth/size/body region phenotype	J:169457
Cdc25a^tm1Kiyo/Cdc25a⁺ Tg(MMTV-Myc)141-3Led/? involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1	normal neoplasm	J:123144
Cdc25a^tm1Kiyo/Cdc25a⁺ Tg(MMTV-vHaras)SH1Led/? involves: 129/Sv * C57BL/6 * C57BL/6J * CD-1	decreased incidence of induced tumors	J:123144
Cdc25a^tm1Kiyo/Cdc25a⁺ Tg(MMTV-Erbb2)NK1Mul/? involves: 129/Sv * C57BL/6 * FVB/N	decreased cell proliferation	J:123144
	decreased incidence of induced tumors	J:123144

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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