Mtnr1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mtnr1a
melatonin receptor 1A
MGI:102967

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mtnr1a^em1Stko/Mtnr1a⁺ involves: C57BL/6 * CBA/J	abnormal osteoblast physiology	J:370727
	abnormal trabecular bone morphology	J:370727
	decreased bone mass	J:370727
	decreased bone mineralization	J:370727
	decreased bone ossification	J:370727
	decreased bone trabecula number	J:370727
	decreased bone volume	J:370727
	decreased osteoblast cell number	J:370727
	decreased osteoblast proliferation	J:370727
	impaired osteoblast differentiation	J:370727
	increased bone resorption	J:370727
	increased osteoclast cell number	J:370727
	increased urine calcium level	J:370727
Mtnr1a^tm1Rep/Mtnr1a^tm1Rep involves: 129S4/SvJae * C3Hf/HeA * C57BL/LiA	abnormal electroretinogram waveform feature	J:153084
	decreased a-wave amplitude	J:153084
	decreased b-wave amplitude	J:153084
	decreased retina ganglion cell number	J:153084
	retina photoreceptor degeneration	J:153084
	short photoreceptor inner segment	J:153084
	short photoreceptor outer segment	J:153084
Mtnr1a^tm1Rep/Mtnr1a^tm1Rep involves: 129S4/SvJae * C57BL/6	abnormal neuron physiology	J:41859

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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