Cst3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cst3
cystatin C
MGI:102519

10 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cst3^{tm1(CST3L68Q)Cnw}/Cst3⁺ involves: 129P2/OlaHsd C57BL/6	abnormal male germ cell morphology	J:210672
	amyloidosis	J:210672
	asthenozoospermia	J:210672
	impaired binding of sperm to zona pellucida	J:210672
	reduced male fertility	J:210672
Cst3^{tm1b(EUCOMM)Wtsi}/Cst3⁺ C57BL/6N-Cst3^{tm1b(EUCOMM)Wtsi}/Ucd	small superior vagus ganglion	J:211773
Cst3^tm1Karl/Cst3^tm1Karl involves: 129S/SvEv * C57BL/6	increased metastatic potential	J:62407
Cst3^tm1Karl/Cst3^tm1Karl involves: 129S/SvEv * C57BL/6J * CBA	decreased susceptibility to ischemic brain injury	J:93568
	increased cerebral infarct size	J:93568
	loss of hippocampal neurons	J:93568

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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