GO Annotations Graph

• Symbol: Ppm1a
• Name: protein phosphatase 1A, magnesium dependent, alpha isoform
• ID: MGI:99878

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	ISO	J:164563
Molecular Function	GO:0043169	cation binding	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	IEA	J:72247
Molecular Function	GO:0030145	manganese ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017018	myosin phosphatase activity	IEA	J:72245
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:155856
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:194018
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:217224
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:217224
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:217224
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:86934
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IDA	J:194018
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	ISO	J:164563
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IBA	J:265628
Molecular Function	GO:0070412	R-SMAD binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:194018
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:194018
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:176254
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	IDA	J:176254
Biological Process	GO:0016311	dephosphorylation	ISO	J:164563
Biological Process	GO:0006499	N-terminal protein myristoylation	IDA	J:194018
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IMP	J:217224
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IBA	J:265628
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	ISO	J:164563
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	IBA	J:265628
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0046827	positive regulation of protein export from nucleus	IMP	J:217224
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:194018
Biological Process	GO:0006470	protein dephosphorylation	IMP	J:217224
Biological Process	GO:0006470	protein dephosphorylation	IDA	J:86943
Biological Process	GO:0006611	protein export from nucleus	IMP	J:217224