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GO Annotations Graph
Symbol
Name
ID
Itpr2
inositol 1,4,5-triphosphate receptor 2
MGI:99418

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005262calcium channel activityIEAJ:72247
Molecular FunctionGO:0005262calcium channel activityIEAJ:60000
Molecular FunctionGO:0005509calcium ion bindingISOJ:155856
Molecular FunctionGO:0015278calcium-release channel activityIDAJ:19925
Molecular FunctionGO:0070679inositol 1,4,5 trisphosphate bindingISOJ:155856
Molecular FunctionGO:0070679inositol 1,4,5 trisphosphate bindingIBAJ:265628
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityISOJ:155856
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIBAJ:265628
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIDAJ:121270
Molecular FunctionGO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activityIDAJ:19925
Molecular FunctionGO:0005216monoatomic ion channel activityIEAJ:72247
Molecular FunctionGO:0035091phosphatidylinositol bindingIBAJ:265628
Molecular FunctionGO:0035091phosphatidylinositol bindingIDAJ:121270
Molecular FunctionGO:0035091phosphatidylinositol bindingIDAJ:19925
Molecular FunctionGO:0005515protein bindingIPIJ:235425
Molecular FunctionGO:0097110scaffold protein bindingISOJ:164563
Molecular FunctionGO:0044325transmembrane transporter bindingISOJ:164563
Cellular ComponentGO:0030424axonISOJ:155856
Cellular ComponentGO:0005938cell cortexIDAJ:51940
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmIDAJ:51940
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:155856
Cellular ComponentGO:0005783endoplasmic reticulumISOJ:164563
Cellular ComponentGO:0005789endoplasmic reticulum membraneISOJ:155856
Cellular ComponentGO:0005789endoplasmic reticulum membraneIBAJ:265628
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0043209myelin sheathISOJ:155856
Cellular ComponentGO:0005654nucleoplasmISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043235receptor complexISOJ:194542
Cellular ComponentGO:0016529sarcoplasmic reticulumISOJ:155856
Cellular ComponentGO:0016529sarcoplasmic reticulumIBAJ:265628
Cellular ComponentGO:0016529sarcoplasmic reticulumIDAJ:99797
Cellular ComponentGO:0033017sarcoplasmic reticulum membraneISOJ:164563
Cellular ComponentGO:0030667secretory granule membraneIBAJ:265628
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:60000
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:72247
Biological ProcessGO:0006816calcium ion transportIDAJ:19925
Biological ProcessGO:0071320cellular response to cAMPIDAJ:164619
Biological ProcessGO:0071361cellular response to ethanolIMPJ:171210
Biological ProcessGO:0006811monoatomic ion transportIEAJ:72247
Biological ProcessGO:0006811monoatomic ion transportIEAJ:60000
Biological ProcessGO:0051209release of sequestered calcium ion into cytosolISOJ:155856
Biological ProcessGO:0001666response to hypoxiaISOJ:164563
Biological ProcessGO:0055085transmembrane transportIEAJ:72247

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory