GO Annotations Graph

• Symbol: Rasa1
• Name: RAS p21 protein activator 1
• ID: MGI:97860

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:155856
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:155856
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005161	platelet-derived growth factor receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:40721
Molecular Function	GO:0005515	protein binding	IPI	J:43960
Molecular Function	GO:0043422	protein kinase B binding	ISO	J:155856
Molecular Function	GO:1990782	protein tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-4093335
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:98043
Cellular Component	GO:0001726	ruffle	IDA	J:98043
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:155856
Biological Process	GO:0048514	blood vessel morphogenesis	ISO	J:164563
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:155856
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:0046326	positive regulation of glucose import	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0030833	regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0007165	signal transduction	ISO	J:164563