GO Annotations Graph

• Symbol: Ptprz1
• Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
• ID: MGI:97816

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0016791	phosphatase activity	ISO	J:155856
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:84104
Molecular Function	GO:0005515	protein binding	IPI	J:84104
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:155856
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	IMP	J:107976
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0031012	extracellular matrix	IDA	J:146166
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0030175	filopodium	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0072534	perineuronal net	ISO	J:155856
Cellular Component	GO:0072534	perineuronal net	IDA	J:62139
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:236151
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0032587	ruffle membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:263376
Cellular Component	GO:0045202	synapse	EXP	J:263376
Biological Process	GO:0007413	axonal fasciculation	ISO	J:155856
Biological Process	GO:0007409	axonogenesis	IDA	J:54926
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:202604
Biological Process	GO:0007611	learning or memory	IMP	J:107976
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:155856
Biological Process	GO:2000171	negative regulation of dendrite development	ISO	J:155856
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:273584
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:177481
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	ISO	J:155856
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	IMP	J:107976
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	IBA	J:265628
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:155856
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:2001224	positive regulation of neuron migration	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	ISO	J:155856
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:1900149	positive regulation of Schwann cell migration	ISO	J:155856
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:155856
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0031641	regulation of myelination	IMP	J:236151
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	IMP	J:177481