GO Annotations Graph

• Symbol: Npr3
• Name: natriuretic peptide receptor 3
• ID: MGI:97373

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031404	chloride ion binding	ISO	J:164563
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	ISO	J:155856
Molecular Function	GO:0042562	hormone binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0016941	natriuretic peptide receptor activity	ISO	J:155856
Molecular Function	GO:0016941	natriuretic peptide receptor activity	ISO	J:164563
Molecular Function	GO:0016941	natriuretic peptide receptor activity	IBA	J:265628
Molecular Function	GO:0042277	peptide binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:164563
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:155856
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IMP	J:287812
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:287812
Biological Process	GO:0007194	negative regulation of adenylate cyclase activity	ISO	J:155856
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:184488
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0002158	osteoclast proliferation	IMP	J:56058
Biological Process	GO:0030157	pancreatic juice secretion	ISO	J:155856
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	ISO	J:155856
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	ISO	J:155856
Biological Process	GO:0035810	positive regulation of urine volume	IMP	J:56058
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:56058
Biological Process	GO:0008217	regulation of blood pressure	ISO	J:155856
Biological Process	GO:0033688	regulation of osteoblast proliferation	IMP	J:56058
Biological Process	GO:0002931	response to ischemia	IMP	J:287812
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:56058
Biological Process	GO:0001501	skeletal system development	IDA	J:56058
Biological Process	GO:0042311	vasodilation	ISO	J:155856