Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including chloride ion binding activity; peptide receptor activity; and protein homodimerization activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; osteoclast proliferation; and response to ischemia. Predicted to be located in plasma membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including central nervous system; gut; heart and pericardium; lung; and urinary system. Used to study bone disease. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3).